Wang Yanli, Wang Yuguang, Liang Qiande, Ma Zengchun, Xiao Chengrong, Tan Hongling, Gao Yue
PLA General Hospital, Beifing 100853, China.
Zhongguo Zhong Yao Za Zhi. 2012 Jul;37(14):2139-42.
The compatible use of Veratrum nigrum with asarum, is one of the eighteen incompatible pairs. To research the toxic regularity of the compatible use of V. nigrum and asarum, this experiment adopted the uniform design combining with acute toxicity test, with the number of died animals as the observation indicator. The results showed that the toxicity came from the common effect of V. nigrum and asarum, and V. nigrum after the compatible use, and V. nigrum made a greater contribution to the toxicity caused by the compatible use. But the toxicity did not absolutely enhance with the increase in use of V. nigrum.
藜芦与细辛配伍使用，是十八反之一。为研究藜芦与细辛配伍使用的毒性规律，本实验采用均匀设计结合急性毒性试验，以动物死亡数为观察指标。结果表明，毒性来自藜芦与细辛的共同作用，且配伍后的藜芦对配伍所致毒性贡献更大。但毒性并非随藜芦用量增加而绝对增强。
