Division of Neonatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143-0734, USA.
Pediatrics. 2012 Dec;130(6):e1679-87. doi: 10.1542/peds.2012-0547. Epub 2012 Nov 5.
To evaluate a multihospital collaborative designed to increase breast milk feeding in premature infants.
Eleven NICUs in the California Perinatal Quality of Care Collaborative participated in an Institute for Healthcare Improvement-style collaborative to increase NICU breast milk feeding rates. Multiple interventions were recommended with participating sites implementing a self-selected combination of these interventions. Breast milk feeding rates were compared between baseline (October 2008-September 2009), implementation (October 2009-September 2010), and sustainability periods (October 2010-March 2011). Secondary outcome measures included necrotizing enterocolitis (NEC) rates and lengths of stay. California Perinatal Quality of Care Collaborative hospitals not participating in the project served as a control population.
The breast milk feeding rate in the intervention sites improved from baseline (54.6%) to intervention period (61.7%; P = .005) with sustained improvement over 6 months postintervention (64.0%; P = .003). NEC rates decreased from baseline (7.0%) to intervention period (4.3%; P = .022) to sustainability period (2.4%; P < .0001). Length of stay increased during the intervention but returned to baseline levels in the sustainability period. Control hospitals had higher rates of breast milk feeding at baseline (64.2% control vs 54.6% participants, P < .0001), but over the course of the implementation (65.7% vs 61.7%, P = .049) and sustainability periods (67.7% vs 64.0%, P = .199), participants improved to similar rates as the control group.
Implementation of a breast milk/nutrition change package by an 11-site collaborative resulted in an increase in breast milk feeding and decrease in NEC that was sustained over an 18-month period.
评估一项旨在增加早产儿母乳喂养的多医院合作项目。
加州围产期护理质量合作组织中的 11 家新生儿重症监护病房参与了一项以改善医疗保健协会为风格的合作,以提高新生儿重症监护病房母乳喂养率。建议采取多种干预措施,参与的机构自行选择组合这些干预措施。在基线(2008 年 10 月至 2009 年 9 月)、实施(2009 年 10 月至 2010 年 9 月)和可持续性期间(2010 年 10 月至 2011 年 3 月)比较母乳喂养率。次要结果指标包括坏死性小肠结肠炎(necrotizing enterocolitis,NEC)发生率和住院时间。未参与该项目的加州围产期护理质量合作组织医院作为对照组。
干预组的母乳喂养率从基线(54.6%)提高到干预期(61.7%;P =.005),且在干预后 6 个月内持续改善(64.0%;P =.003)。NEC 发生率从基线(7.0%)降至干预期(4.3%;P =.022),再降至可持续性期间(2.4%;P <.0001)。住院时间在干预期间增加,但在可持续性期间恢复到基线水平。对照组在基线时的母乳喂养率较高(对照组为 64.2%,而参与者为 54.6%,P <.0001),但在实施期间(65.7%对 61.7%,P =.049)和可持续性期间(67.7%对 64.0%,P =.199),参与者的母乳喂养率提高到与对照组相似的水平。
由 11 家合作机构实施母乳喂养/营养方案包,使母乳喂养率提高,坏死性小肠结肠炎减少,在 18 个月的时间内持续存在。