Stokke K T, Enger S C
Scand J Clin Lab Invest. 1979 Nov;39(7):597-600. doi: 10.3109/00365517909108862.
In vitro esterification of plasma cholesterol was measured in twelve healthy subjects, six of whom had high plasma concentrations of high density lipoprotein (HDL) cholesterol, whereas the other six had low concentrations. Irrespective of the method used no difference between the groups with the respect to cholesterol esterification could be demonstrated. This may indicate that the beneficial effect of HDL on the development of atherosclerotic disease works thorugh other mechanisms than by facilitating the transport of cholesterol from peripheral tissues to the liver.
在12名健康受试者中测量了血浆胆固醇的体外酯化，其中6人血浆高密度脂蛋白（HDL）胆固醇浓度高，而另外6人浓度低。无论使用何种方法，两组之间在胆固醇酯化方面均未显示出差异。这可能表明，HDL对动脉粥样硬化疾病发展的有益作用是通过其他机制起作用的，而不是通过促进胆固醇从外周组织向肝脏的转运。
