慢性炎症性脱髓鞘性多发性神经病中的人类白细胞抗原
HLA antigens in chronic inflammatory demyelinating polyneuropathy.
作者信息
Feeney D J, Pollard J D, McLeod J G, Stewart G J, Doran T J
机构信息
Department of Medicine, University of Sydney, New South Wales, Australia.
出版信息
J Neurol Neurosurg Psychiatry. 1990 Feb;53(2):170-2. doi: 10.1136/jnnp.53.2.170.
Abstract
HLA typing of 71 patients with chronic inflammatory demyelinating polyneuropathy (CIDP) showed an overall increase in frequencies of HLA-A3, -B7, -DR2 as well as concomitantly decreased frequencies of HLA-44 and DR7. The strongest associations were seen with HLA-DR2, -DR7 and -B44 in CIDP overall, although they did not reach statistical significance.
摘要
对71例慢性炎症性脱髓鞘性多发性神经病（CIDP）患者进行的HLA分型显示，HLA - A3、- B7、- DR2的频率总体增加，同时HLA - 44和DR7的频率降低。尽管未达到统计学意义，但在CIDP总体中，与HLA - DR2、- DR7和- B44的关联最为明显。
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