临床I-II期乳腺癌保乳手术的结果
Results of breast conserving surgery in clinical stage I-II breast carcinoma.
作者信息
Erdem Erhan, Alagol Haluk
机构信息
Department of 5th General Surgery, Ankara Oncology Training and Research hospital, 13th Street, Demetevler, Ankara, Turkey.
出版信息
Indian J Surg. 2009 Feb;71(1):29-34. doi: 10.1007/s12262-009-0007-6. Epub 2009 Mar 13.
BACKGROUND
The role of breast conserving surgery with radiotherapy is well established and has become a widely used procedure in breast cancer. Patient selection, a multidisciplinary approach, and expert surgical technique are important factors to avoid locoregional recurrence. The aim of this study was to analyse the outcomes of patients treated with breast conserving surgery in stage I-II breast cancer.
METHODS
In this study, the results of 135 breast conserving surgery cases are reported. The majority of patients received radiotherapy and adjuvant systemic treatment.
RESULTS
At a median follow-up period of 54 months, 5 patients (3.7%) developed locoregional recurrence. The 5 years overall and disease-free survival rates were 90% and 84%, respectively. Young age, lymph node involvement, and oestrogen receptor negativity were independent predictors for overall survival.
CONCLUSION
In selected patients, breast conserving surgery using good surgical technique in conjunction with radiotherapy can achieve a high survival rate with a low locoregional recurrence rate.
背景
保乳手术联合放疗的作用已得到充分确立，并且已成为乳腺癌中广泛应用的一种术式。患者选择、多学科方法以及专业的手术技术是避免局部区域复发的重要因素。本研究的目的是分析Ⅰ-Ⅱ期乳腺癌患者接受保乳手术的治疗结果。
方法
在本研究中，报告了135例保乳手术病例的结果。大多数患者接受了放疗和辅助全身治疗。
结果
在中位随访期54个月时，5例患者（3.7%）出现局部区域复发。5年总生存率和无病生存率分别为90%和84%。年轻、淋巴结受累以及雌激素受体阴性是总生存的独立预测因素。
结论
在选定的患者中，采用良好手术技术的保乳手术联合放疗可实现高生存率和低局部区域复发率。
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