Interdisciplinary Management of Pancreatic Cystic Tumors (IMPACT) Clinic, Fish Center for Women's Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA ; Center for Pancreatic Disease, Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Gastroenterol Res Pract. 2012;2012:513163. doi: 10.1155/2012/513163. Epub 2012 Oct 21.
Cystic neoplasms of the pancreas are increasingly recognized due to the frequent use of abdominal imaging. It is reported that up to 20% of abdominal cross-sectional scans identify incidental asymptomatic pancreatic cysts. Proper characterization of pancreatic cystic neoplasms is important not only to recognize premalignant lesions that will require surgical resection, but also to allow nonoperative management of many cystic lesions that will not require resection with its inherent morbidity. Though reliable biomarkers are lacking, a wide spectrum of diagnostic modalities are available to evaluate pancreatic cystic neoplasms, including radiologic, endoscopic, laboratory, and pathologic analysis. An interdisciplinary approach to management of these lesions which incorporates recent, specialty-specific advances in the medical literature is herein suggested.
由于腹部影像学的频繁使用,胰腺囊性肿瘤的检出率逐渐增高。据报道,高达 20%的腹部横断面扫描可发现无症状的偶然胰腺囊肿。对胰腺囊性肿瘤进行准确的特征描述不仅有助于识别需要手术切除的癌前病变,也有助于对许多无需手术切除的囊性病变进行非手术治疗,因为手术切除会带来固有发病率。尽管缺乏可靠的生物标志物,但有一系列的诊断方法可用于评估胰腺囊性肿瘤,包括影像学、内镜、实验室和病理学分析。在此建议采用一种多学科的方法来管理这些病变,该方法综合了医学文献中最近的、具有专业特色的进展。