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孕妇血清锌水平及其与新生儿出生体重的关系。

Maternal serum zinc level and its relation with neonatal birth weight.

作者信息

Naher K, Nahar K, Aziz M A, Hossain A, Rahman R, Yasmin N

机构信息

Mymensingh Medical College, Bangladesh.

出版信息

Mymensingh Med J. 2012 Oct;21(4):588-93.

Abstract

The present study was conducted in the Department of Obstetrics & Gynaecology, Mymensingh Medical College Hospital, Mymensingh and Molecular Microbiology & Central Laboratory of Bangladesh Institute of Nuclear Agriculture (BINA) from 15th November 2007 to 31st May 2009 to find out the relation between maternal serum zinc level with neonatal birth weight. Hundred pregnant women who were advised to take 61.8 mg zinc daily throughout pregnancy were assigned to study group while the pregnant woman did not take zinc orally were allocated into control group. Serum zinc levels were measured between 37-42 weeks gestation and birth weight were measured just after delivery. Data were processed and analyzed using SPSS version 11.5. The test used to analyze the data was descriptive statistics, Chi-square probability test, Pearson correlation, unpaired t-test and odds ratio. A probability value of <0.05 was considered significant. Majority (97%) of the cases who received zinc during their antenatal period had normal serum zinc (≥ 700μg/L) level compared to only 22% of the control group woman who did not receive zinc. Normal birth weight of babies in pregnant woman who received zinc is 5.7 times higher than the pregnant woman who did not receive zinc. As the present study was a cross-sectional one, further study with large sample size and prospective design is recommended.

摘要

本研究于2007年11月15日至2009年5月31日在孟加拉国米门辛希医学院医院妇产科以及孟加拉国核农业研究所(BINA)分子微生物学与中央实验室进行,旨在探究孕妇血清锌水平与新生儿出生体重之间的关系。100名在整个孕期被建议每日摄入61.8毫克锌的孕妇被分配到研究组,而未口服锌的孕妇被分配到对照组。在妊娠37 - 42周期间测量血清锌水平,分娩后立即测量出生体重。使用SPSS 11.5版本对数据进行处理和分析。用于分析数据的检验方法有描述性统计、卡方概率检验、皮尔逊相关性分析、非配对t检验和比值比。概率值<0.05被认为具有显著性。在孕期接受锌补充的大多数(97%)病例血清锌水平正常(≥700μg/L),而未接受锌补充的对照组女性中只有22%血清锌水平正常。接受锌补充的孕妇所生婴儿的正常出生体重比未接受锌补充的孕妇所生婴儿高5.7倍。由于本研究是一项横断面研究,建议进行更大样本量和前瞻性设计的进一步研究。

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