孕期接受锌补充剂与未接受锌补充剂的母亲所生新生儿出生体重的比较。

Comparison of birth weights of neonates of mothers receiving vs. not receiving zinc supplement at pregnancy.

作者信息

Boskabadi Hassan, Maamouri Gholamali, Akhondian Javad, Ashrafzadeh Farah, Boskabadi Abbas, Faramarzi Raheleh, Heidar Elahe, Pourbadakhshan Nafiseh, Shojaei Seyed Reza Habibzadeh, Zakerihamidi Maryam, Vatanchi Atiyeh Mohammadzadeh, Sokhtanloo Mohammad, Razaghi Naghmeh, Kalani Farnaz, Ataei Hosein, Darabi Azadeh, Mousavi Mojgan Sadat, Hakimiakhangan Saeideh, Bagheri Fathemeh

机构信息

Department of Pediatrics, Faculty of Medicine, Mashhad University o Medical Sciences, Mashhad, Iran.

Department of Orthopedic Surgeon, Faculty of Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

BMC Pregnancy Childbirth. 2021 Mar 6;21(1):187. doi: 10.1186/s12884-021-03598-8.

DOI:10.1186/s12884-021-03598-8

PMID:33676424

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7936407/

Abstract

BACKGROUND

Zinc is an essential element for normal embryogenesis and embryonic and neonatal development. Therefore, we compared the birth weights of neonates born to mothers who consumed zinc supplement during pregnancy with that of neonates born to mothers who did not.

METHODS

In a cross-sectional study, we divided 200 pregnant mothers into two groups: case group (mothers receiving zinc supplement during pregnancy) and control group (mothers not receiving zinc supplement during pregnancy) Then, the neonate's cord zinc level and mother's serum level were measured and neonate's growth charts (weight, height and head circumference)were completed.

RESULTS

In this study, both groups of mothers were observed to have zinc deficiency; 35% of the mothers who consumed zinc supplements and 81% of the mothers who did not consume zinc supplements (P < 0.001). Based on the results, maternal serum of zinc (P < 0.001), neonatal birth weight (P = 0.008), maternal age (P < 0.001) and parity (P < 0.01) in zinc-supplemented group were higher. Neonatal birth weight was associated moderately with mother's zinc serum levels and poorly with neonatal serum zinc levels.

CONCLUSION

Zinc consumption during pregnancy increases serum zinc level of mother and neonatal weight. Neonatal weight has a higher correlation to maternal serum zinc level.

摘要

背景

锌是正常胚胎发生以及胚胎和新生儿发育所必需的元素。因此，我们比较了孕期服用锌补充剂的母亲所生新生儿的出生体重与未服用锌补充剂的母亲所生新生儿的出生体重。

方法

在一项横断面研究中，我们将200名孕妇分为两组：病例组（孕期接受锌补充剂的母亲）和对照组（孕期未接受锌补充剂的母亲）。然后，测量新生儿的脐带锌水平和母亲的血清水平，并完成新生儿的生长图表（体重、身高和头围）。

结果

在本研究中，两组母亲均存在锌缺乏；服用锌补充剂的母亲中有35%，未服用锌补充剂的母亲中有81%（P<0.001）。基于结果，补充锌组的母亲血清锌水平（P<0.001）、新生儿出生体重（P=0.008）、母亲年龄（P<0.001）和产次（P<0.01）更高。新生儿出生体重与母亲的锌血清水平呈中度相关，与新生儿血清锌水平相关性较差。