Parra R O, Gregory J G
Department of Surgery, St. Louis University Medical Center, Missouri.
J Urol. 1990 Apr;143(4):753-4. doi: 10.1016/s0022-5347(17)40081-4.
The occurrence of hot flashes in men after bilateral orchiectomy for prostatic carcinoma can be bothersome and difficult to treat. Transdermal clonidine was administered to 7 patients with such symptoms. In 3 patients the hot flashes were ablated and in the remaining 4 the number and frequency of attacks were considerably reduced. No significant side effects were encountered. We suggest that transdermal clonidine (0.1 mg.) administered weekly can safely control undesirable hot flashes in men after bilateral orchiectomy.
前列腺癌患者双侧睾丸切除术后男性出现潮热可能令人烦恼且难以治疗。对7例有此类症状的患者给予经皮可乐定治疗。3例患者潮热消失,其余4例发作次数和频率显著减少。未出现明显副作用。我们建议每周给予经皮可乐定(0.1毫克)可安全控制双侧睾丸切除术后男性不良潮热。