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儿童头皮孤立性纤维瘤

Solitary fibrous tumor of the scalp in a child.

作者信息

Rizk Tony, Awada Adnan, Sebaaly Amer, Hourani Roula

机构信息

Department of Neurosurgery, Hotel Dieu de France.

出版信息

J Neurosurg Pediatr. 2013 Jan;11(1):79-81. doi: 10.3171/2012.10.PEDS11250. Epub 2012 Nov 9.

Abstract

Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that arise most commonly in the pleura but have been increasingly reported in extrapleural sites. The authors report the case of an SFT of the scalp that manifested as an enlarging scalp mass in a 2-year-old boy. The mass was surgically excised. Histological examination showed it to be composed of fusiform cells of variable cellularity with a central hyalinization zone. Immunohistochemical staining was positive for CD34 and negative for smooth muscle actin, S100 protein, desmin, and h-caldesmon. On 1-year follow-up, there was no recurrence of the mass. This case presented some diagnostic difficulty because of the wide range of possible diagnoses for a pediatric scalp mass; however, the distinct immunohistochemical profile helped to eliminate other more frequent fibrous tumors of the scalp. The behavior of scalp SFTs is usually benign, but their course can be unpredictable, and recognition of these lesions is essential.

摘要

孤立性纤维性肿瘤(SFTs)是一种罕见的间叶性肿瘤,最常发生于胸膜,但在胸膜外部位的报道也日益增多。作者报告了一例头皮SFTs病例,该病例表现为一名2岁男孩头皮肿物逐渐增大。肿物经手术切除。组织学检查显示其由细胞密度各异的梭形细胞组成,并有一个中央透明化区域。免疫组化染色显示CD34阳性,平滑肌肌动蛋白、S100蛋白、结蛋白和h - 钙调蛋白阴性。随访1年,肿物无复发。由于小儿头皮肿物的可能诊断范围广泛,该病例存在一定的诊断困难;然而,独特的免疫组化特征有助于排除其他更常见的头皮纤维性肿瘤。头皮SFTs的行为通常为良性,但其病程可能不可预测,认识这些病变至关重要。

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