Rouanet J M, Besançon P
Ann Nutr Aliment. 1979;33(3):405-16.
A phytohemagglutinin extract is prepared from raw kidney beans (Phaseolus vulgaris) and incorporated at a level of 1% (dry matter) in the diet of young growing rats. Beside a decrease of feed intakes, the main effects of the experimental diet are the following : growth depression, decrease of dry matter and protein digestibility and hypoglycemia. Biological value, organs weight (liver, kidneys, spleen) did not change significantly. The hemagglutinin extract induces an inhibition of saccharase activity whereas (Na+-K+)-ATPase remains unchanged. Growth depressing effect may be due to an alteration of hydrolysis and absorption mechanisms at the level of brush border of enterocytes.
从生芸豆（菜豆）中制备植物血凝素提取物，并以1%（干物质）的水平添加到幼年生长大鼠的日粮中。除了采食量下降外，实验日粮的主要影响如下：生长抑制、干物质和蛋白质消化率降低以及低血糖。生物学价值、器官重量（肝脏、肾脏、脾脏）没有显著变化。血凝素提取物会抑制蔗糖酶活性，而（钠-钾）-ATP酶保持不变。生长抑制作用可能是由于肠细胞刷状缘水平的水解和吸收机制发生改变。
