• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

植物血凝素对大鼠小肠绒毛-隐窝轴上刷状缘水解酶的选择性作用。

Selective effects of PHA on rat brush border hydrolases along the crypt-villus axis.

作者信息

Rouanet J M, Lafont J, Zambonino-Infante J L, Besançon P

机构信息

Laboratoire de Physiologie de la Nutrition, Centre de Génie et Technologie Alimentaires, Montpellier, France.

出版信息

Experientia. 1988 Apr 15;44(4):340-1. doi: 10.1007/BF01961274.

DOI:10.1007/BF01961274
PMID:3360085
Abstract

The mechanism of the toxicity of lectin from Phaseolus vulgaris seeds has been investigated on rat enterocytes. Cell isolation procedures showed a selectivity in the loss of brush border hydrolases; this indicated that the microvilli blebbing was not the only mechanism of action of lectins on rat enterocytes.

摘要

菜豆种子凝集素的毒性机制已在大鼠肠上皮细胞中进行了研究。细胞分离程序显示在刷状缘水解酶的损失方面存在选择性；这表明微绒毛泡化不是凝集素对大鼠肠上皮细胞作用的唯一机制。

相似文献

1
Selective effects of PHA on rat brush border hydrolases along the crypt-villus axis.植物血凝素对大鼠小肠绒毛-隐窝轴上刷状缘水解酶的选择性作用。
Experientia. 1988 Apr 15;44(4):340-1. doi: 10.1007/BF01961274.
2
Interaction of the brush-border hydrolases of the human small intestine with lectins.
Digestion. 1983;27(1):1-7. doi: 10.1159/000198912.
3
Duodenal toxicity of dietary Phaseolus vulgaris lectins in the rat: an integrative assay.
Digestion. 1988;41(2):83-93. doi: 10.1159/000199736.
4
Effect of hormones on the development of various brush border enzymes across crypt-villus axis in rat intestine.激素对大鼠肠道隐窝-绒毛轴上各种刷状缘酶发育的影响。
Indian J Med Res. 1988 Aug;88:169-74.
5
Effect of lectins from leguminous seeds on rat duodenal enterokinase activity.
Experientia. 1983 Dec 15;39(12):1356-8. doi: 10.1007/BF01990102.
6
Effect of restricted feeding on circadian rhythmicity of intestinal brush border hydrolases & nutrient uptake in pigeons.限食对鸽子肠道刷状缘水解酶昼夜节律及营养物质吸收的影响。
Indian J Exp Biol. 1983 Nov;21(11):600-3.
7
Actinomycin D suppresses hydrocortisone-induced changes in distribution and sialylation of brush-border enzymes in jejunal villi and crypts.放线菌素D可抑制氢化可的松诱导的空肠绒毛和隐窝刷状缘酶分布及唾液酸化的变化。
Biochem Int. 1990;21(3):581-91.
8
Expression of brush border enzymes in ethanol fed rat intestine.乙醇喂养大鼠肠道中刷状缘酶的表达。
Indian J Med Res. 1994 Dec;100:289-94.
9
Age related increase of brush border enzyme activities along the small intestine.小肠中刷状缘酶活性随年龄增长而增加。
Gut. 1988 Nov;29(11):1557-63. doi: 10.1136/gut.29.11.1557.
10
Peroxisomes and peroxisomal enzymes along the crypt-villus axis of the rat intestine.大鼠肠道隐窝-绒毛轴上的过氧化物酶体和过氧化物酶体酶
Differentiation. 1993 Sep;54(2):99-108. doi: 10.1111/j.1432-0436.1993.tb00712.x.

本文引用的文献

1
A method for the rapid determination of alkaline phosphates with five cubic millimeters of serum.一种用五立方毫米血清快速测定碱性磷酸酶的方法。
J Biol Chem. 1946 Jul;164:321-9.
2
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
3
In vivo responses of rat intestinal epithelium to intraluminal dietary lectins.大鼠肠上皮对肠腔内膳食凝集素的体内反应。
Gastroenterology. 1982 May;82(5 Pt 1):838-48.
4
A method for the separate assay of "neutral" and "acid" beta-galactosidase in homogenates of rat small-intestinal mucosa.一种用于单独测定大鼠小肠黏膜匀浆中“中性”和“酸性”β-半乳糖苷酶的方法。
Anal Biochem. 1969 Mar;27(3):409-18. doi: 10.1016/0003-2697(69)90054-2.
5
Assay of intestinal disaccharidases.肠道双糖酶测定
Anal Biochem. 1968 Jan;22(1):99-107. doi: 10.1016/0003-2697(68)90263-7.
6
The aminopeptidase from hog intestinal brush border.来自猪小肠刷状缘的氨肽酶。
Biochim Biophys Acta. 1973 Sep 15;321(1):282-95. doi: 10.1016/0005-2744(73)90083-1.
7
Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation.肠上皮细胞表面膜糖蛋白的合成。I. 细胞分化的一个指标。
J Biol Chem. 1973 Apr 10;248(7):2536-41.
8
Purification of the phytohemagglutinin family of proteins from red kidney beans (Phaseolus vulgaris) by affinity chromatography.通过亲和色谱法从红芸豆（菜豆）中纯化植物血凝素蛋白家族。
Biochim Biophys Acta. 1975 Sep 9;405(1):72-81. doi: 10.1016/0005-2795(75)90316-5.
9
Intestinal enzymes activities in isolated villus and crypt cells during postnatal development of the rat.大鼠出生后发育过程中分离的绒毛和隐窝细胞中的肠道酶活性。
Cell Tissue Res. 1977 Jan 12;176(2):167-78. doi: 10.1007/BF00229460.
10
[Effects of a phytohemagglutinin extract on growth, nitrogen digestibility and the activity of invertase and (Na+-K+)-ATPase in the intestinal mucosa of the rat].[植物血凝素提取物对大鼠生长、氮消化率及肠黏膜中转化酶和（钠 - 钾）-ATP酶活性的影响]
Ann Nutr Aliment. 1979;33(3):405-16.