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吡格列酮治疗 3 个月可降低 2 型糖尿病患者循环 C1q 结合型脂联素复合物与总脂联素的比值，而体重指数无变化。

Three-month treatment with pioglitazone reduces circulating C1q-binding adiponectin complex to total-adiponectin ratio, without changes in body mass index, in people with type 2 diabetes.

机构信息

Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.

出版信息

Diabetes Res Clin Pract. 2013 Jan;99(1):e14-7. doi: 10.1016/j.diabres.2012.10.003. Epub 2012 Nov 9.

DOI:10.1016/j.diabres.2012.10.003
PMID:23142017
Abstract

We measured circulating C1q-binding adiponectin (C1q-APN) levels before and after 3-month treatment with pioglitazone in people with type 2 diabetes. The results indicate 3-month treatment with pioglitazone reduces circulating levels of C1q-APN/total-adiponectin ratio without changes in body mass index.

摘要

我们在 2 型糖尿病患者接受吡格列酮治疗 3 个月前后测量了循环 C1q 结合脂联素（C1q-APN）水平。结果表明，吡格列酮治疗 3 个月可降低循环 C1q-APN/总脂联素比值，而体重指数无变化。

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1
Three-month treatment with pioglitazone reduces circulating C1q-binding adiponectin complex to total-adiponectin ratio, without changes in body mass index, in people with type 2 diabetes.吡格列酮治疗 3 个月可降低 2 型糖尿病患者循环 C1q 结合型脂联素复合物与总脂联素的比值，而体重指数无变化。
Diabetes Res Clin Pract. 2013 Jan;99(1):e14-7. doi: 10.1016/j.diabres.2012.10.003. Epub 2012 Nov 9.
2
Withdrawal of pioglitazone in patients with type 2 diabetes mellitus.吡格列酮治疗 2 型糖尿病患者的停药。
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Effects of sitagliptin or metformin added to pioglitazone monotherapy in poorly controlled type 2 diabetes mellitus patients.吡格列酮单药治疗控制不佳的 2 型糖尿病患者中加用西格列汀或二甲双胍的效果。
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Three-month treatment with pioglitazone reduces circulating levels of S100A8/A9 (MRP8/14) complex, a biomarker of inflammation, without changes in body mass index, in type 2 diabetics with abdominal obesity.吡格列酮治疗 3 个月可降低炎症生物标志物 S100A8/A9（MRP8/14）复合物的循环水平，而不改变腹型肥胖 2 型糖尿病患者的体重指数。
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Comparison of the effects of pioglitazone and voglibose on circulating total and high-molecular-weight adiponectin, and on two fibrinolysis inhibitors, in patients with Type 2 diabetes.吡格列酮与伏格列波糖对2型糖尿病患者循环中总脂联素和高分子量脂联素以及两种纤溶抑制剂影响的比较
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Three-month treatment with pioglitazone reduces circulating levels of thiobarbituric acid-reacting substances, a marker of reactive oxidative stress, without change in body mass index, in Japanese patients with type 2 diabetes.在日本2型糖尿病患者中，使用吡格列酮进行为期三个月的治疗可降低硫代巴比妥酸反应物质（一种反应性氧化应激标志物）的循环水平，且体重指数无变化。
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