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吡格列酮治疗 3 个月可降低炎症生物标志物 S100A8/A9（MRP8/14）复合物的循环水平，而不改变腹型肥胖 2 型糖尿病患者的体重指数。

Three-month treatment with pioglitazone reduces circulating levels of S100A8/A9 (MRP8/14) complex, a biomarker of inflammation, without changes in body mass index, in type 2 diabetics with abdominal obesity.

机构信息

Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Osaka, Japan.

出版信息

Diabetes Res Clin Pract. 2012 Mar;95(3):e58-60. doi: 10.1016/j.diabres.2011.11.018. Epub 2011 Dec 9.

DOI:10.1016/j.diabres.2011.11.018
PMID:22154375
Abstract

We measured circulating S100A8/A9 (MRP8/14) complex levels before and after 3-month treatment with pioglitazone in type 2 diabetic patients. The results showed that pioglitazone reduced circulating S100A8/A9 complex levels, without changing body mass index, in type 2 diabetic patients with abdominal obesity.

摘要

我们在 2 型糖尿病患者接受吡格列酮治疗 3 个月前后测量了循环 S100A8/A9（MRP8/14）复合物水平。结果表明，吡格列酮降低了腹型肥胖 2 型糖尿病患者的循环 S100A8/A9 复合物水平，而体重指数没有变化。

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