Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri 63110, USA.
Curr Opin Pulm Med. 2013 Jan;19(1):49-53. doi: 10.1097/MCP.0b013e32835b117a.
Although current asthma guidelines stress the importance of assessing and enhancing adherence to asthma treatment, medication adherence rates in asthma patients are consistently low in practice. In this review, we summarize current literature on method of measurement, prevalence, outcome and intervention of medication adherence in asthma patients.
Nonadherence to prescribed treatment continues to be a frequent problem in patients with asthma even in recent years. Objective measurement of adherence should be implemented whenever possible. Review of pharmacy refill data or electronic monitoring of inhaler actuation may be a preferred method to assess adherence. Educational programmes should be specifically designed to address the unmet need and specific reasons for nonadherence for the target population. Large, well designed clinical trials to assess the efficacy of remote electronic monitoring and reminder systems to improve adherence are needed.
There is an urgent clinical need for systematic, proven methods to assess and address medication nonadherence in asthma patients.
尽管目前的哮喘指南强调了评估和提高哮喘治疗依从性的重要性,但哮喘患者的药物依从率在实践中始终较低。在这篇综述中,我们总结了目前关于哮喘患者药物依从性的测量方法、患病率、结果和干预措施的文献。
即使在最近几年,不遵医嘱用药在哮喘患者中仍然是一个常见的问题。只要有可能,就应实施对依从性的客观测量。审查药房补充数据或电子监测吸入器的触发可能是评估依从性的首选方法。教育计划应专门针对目标人群的未满足需求和不依从的具体原因进行设计。需要进行大型、精心设计的临床试验,以评估远程电子监测和提醒系统改善依从性的疗效。
迫切需要系统、经过验证的方法来评估和解决哮喘患者的药物不依从问题。