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哮喘和过敏患者的患者报告药物相关问题是否存在差异?芬兰社区药房调查。

Are there differences in the patient-reported medication-related problems among asthma and allergy patients? A community pharmacy survey in Finland.

机构信息

Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.

Biostatistics Unit, University of Helsinki, Helsinki University Hospital, Helsinki, Finland.

出版信息

BMC Public Health. 2023 Aug 18;23(1):1570. doi: 10.1186/s12889-023-16423-y.

DOI:10.1186/s12889-023-16423-y
PMID:37596587
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10436668/
Abstract

BACKGROUND

A medication-related problem is an event involving medication that interferes with desired health outcomes. Those are largely studied among asthma patients, but little is known about medication-related problems among allergy patients. The objective of this study was to determine the most common patient-reported medication-related problems among asthma patients compared to allergy patients during the self-management of diseases. The other objective was to identify how demographic variables and the received treatment information influence reported problems.

METHODS

A nationwide survey was conducted in Finnish community pharmacies (n = 785) in September 2016. The survey targeted patients buying prescription medicines for asthma or allergy.

RESULTS

Responses were received from 46% of targeted pharmacies from 956 respondents. At least one medication problem was reported by 24% of asthma patients and 12% of allergy patients. The most common problems among asthma patients were having problems taking medicines on time (16%), problems in the administration technique (7%) and in the use of the inhaler (4%). Among allergy patients, 10% reported problems remembering to take medicines on time. Severe asthma and allergy increased the risk for medication-related problems (OR 1.20, 95% CI 1.04-1.40 and OR 1.17, 95% CI 1.0-1.37). A higher age and less education were associated with fewer reported medication-related problems among both patient groups.

CONCLUSIONS

Asthma patients reported more medication-related problems than allergy patients. Among both investigated patient groups, remembering to take medicines on time was the most common. Health care professionals should educate younger patients but also older and less educated asthma and allergy patients to recognize and, to solve medication-related problems. In addition, severe asthma patients still need medication counseling.

摘要

背景

药物相关问题是指与药物相关的事件,这些事件会干扰预期的健康结果。这些问题在哮喘患者中得到了广泛研究,但对于过敏患者的药物相关问题知之甚少。本研究的目的是确定在自我管理疾病期间,与哮喘患者相比,过敏患者报告的最常见药物相关问题。另一个目的是确定人口统计学变量和所接受的治疗信息如何影响报告的问题。

方法

2016 年 9 月,在芬兰社区药房进行了一项全国性调查(n=785)。该调查针对购买用于哮喘或过敏的处方药物的患者。

结果

从 956 名受访者中,有 46%的目标药店回复了调查。至少有一个药物问题的报告率在哮喘患者中为 24%,在过敏患者中为 12%。哮喘患者最常见的问题是按时服药有困难(16%)、给药技术问题(7%)和吸入器使用问题(4%)。在过敏患者中,有 10%的人报告说有时会忘记按时服药。严重哮喘和过敏会增加药物相关问题的风险(OR 1.20,95%CI 1.04-1.40 和 OR 1.17,95%CI 1.0-1.37)。较高的年龄和较低的教育程度与两个患者群体中报告的药物相关问题较少有关。

结论

哮喘患者报告的药物相关问题多于过敏患者。在这两个被调查的患者群体中,按时服药是最常见的问题。医疗保健专业人员应该教育年轻患者,但也应该教育哮喘和过敏患者,尤其是年龄较大和受教育程度较低的患者,以识别和解决药物相关问题。此外,严重哮喘患者仍需要药物咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab0/10436668/1f8fa6925f09/12889_2023_16423_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab0/10436668/0348faa619dc/12889_2023_16423_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab0/10436668/1f8fa6925f09/12889_2023_16423_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab0/10436668/0348faa619dc/12889_2023_16423_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab0/10436668/1f8fa6925f09/12889_2023_16423_Fig2_HTML.jpg

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本文引用的文献

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Effectiveness of inhalation technique assessment service for patients with Respimat® inhaler.Respimat® 吸入器吸入技术评估服务对患者的疗效。
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Factors Contributing to Medication Adherence in Patients with a Chronic Condition: A Scoping Review of Qualitative Research.
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Pharmaceutics. 2021 Jul 20;13(7):1100. doi: 10.3390/pharmaceutics13071100.
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