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具有高光热转换效率的均一聚吡咯纳米粒子用于癌症细胞的光热消融。

Uniform polypyrrole nanoparticles with high photothermal conversion efficiency for photothermal ablation of cancer cells.

机构信息

School of Life Science and Technology, State Key Laboratory of Urban Water Resources and Environment, Harbin Institute of Technology, China.

出版信息

Adv Mater. 2013 Feb 6;25(5):777-82. doi: 10.1002/adma.201202211. Epub 2012 Nov 12.

Abstract

Uniform polypyrrole (PPy) nanoparticles are fabricated from a facile one-step aqueous dispersion polymerization. Owing to their high photothermal conversion efficiency and photostability compared with the well-known Au nanorods, as well as their good colloidal stability and biocompatibility, the resulting PPy nanoparticles can used as a novel promising photothermal ablation coupling agent for targeted treatment of cancer.

摘要

采用简便的一步水相分散聚合方法制备了均一的聚吡咯(PPy)纳米粒子。与众所周知的金纳米棒相比,由于其具有较高的光热转换效率和光稳定性,以及良好的胶体稳定性和生物相容性,所得 PPy 纳米粒子可用作新型有前途的光热消融偶联剂,用于癌症的靶向治疗。

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