Department of Biotechnology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Curr Opin Biotechnol. 2013 Jun;24(3):516-25. doi: 10.1016/j.copbio.2012.10.012. Epub 2012 Nov 9.
Microbial life in extreme environments is attracting broad scientific interest. Knowledge about it helps in defining the boundaries for life to exist, and organisms living under extreme conditions are also interesting sources for enzymes with unusual and desirable properties. The tremendous progress in DNA sequencing technologies now makes it relatively easy to gain a representative overview of the composition of such communities, and many community studies have in the last decade applied metagenomics to characterize habitats extreme in, for example, temperature, salt and acidity. The future challenges in the field are likely to become more and more related to the conversion of the expected massive amounts of sequence information into an understanding of the corresponding biological community functions.
极端环境中的微生物生命正引起广泛的科学关注。对其的了解有助于界定生命存在的界限,而在极端条件下生存的生物也是具有独特和理想特性的酶的有趣来源。DNA 测序技术的巨大进步使得相对容易获得这些群落组成的代表性概述,并且在过去十年中,许多群落研究已经应用宏基因组学来描述例如温度、盐度和酸度等极端生境。该领域未来的挑战可能越来越与将预期的大量序列信息转化为对相应生物群落功能的理解相关。