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Psychosis is emerging as a learning and memory disorder.

作者信息

Tamminga Carol A

机构信息

Department of Psychiatry, UT Southwestern Medical School, Dallas, TX, USA.

出版信息

Neuropsychopharmacology. 2013 Jan;38(1):247. doi: 10.1038/npp.2012.187.

DOI:10.1038/npp.2012.187
PMID:23147488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3521988/
Abstract
摘要

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本文引用的文献

1
Memory generalization is selectively altered in the psychosis dimension.记忆泛化在精神病维度上选择性地改变。
Schizophr Res. 2012 Jun;138(1):74-80. doi: 10.1016/j.schres.2012.04.004. Epub 2012 Apr 30.
2
Optogenetic stimulation of a hippocampal engram activates fear memory recall.光遗传学刺激海马体的记忆痕迹会激活恐惧记忆的回忆。
Nature. 2012 Mar 22;484(7394):381-5. doi: 10.1038/nature11028.
3
The hippocampal formation in schizophrenia.精神分裂症的海马结构。
Am J Psychiatry. 2010 Oct;167(10):1178-93. doi: 10.1176/appi.ajp.2010.09081187. Epub 2010 Sep 1.
4
Target-cell-dependent plasticity within the mossy fibre-CA3 circuit reveals compartmentalized regulation of presynaptic function at divergent release sites.苔藓纤维-CA3回路中靶细胞依赖性可塑性揭示了不同释放位点突触前功能的分区调节。
J Physiol. 2008 Mar 15;586(6):1495-502. doi: 10.1113/jphysiol.2007.148635. Epub 2007 Dec 13.
5
Cholinergic suppression of glutamatergic synaptic transmission in hippocampal region CA3 exhibits laminar selectivity: Implication for hippocampal network dynamics.海马体CA3区谷氨酸能突触传递的胆碱能抑制表现出层状选择性：对海马体网络动力学的影响。
Neuroscience. 2007 Nov 23;149(4):760-7. doi: 10.1016/j.neuroscience.2007.07.007. Epub 2007 Jul 12.
6
Metaplasticity: the plasticity of synaptic plasticity.元可塑性：突触可塑性的可塑性。
Trends Neurosci. 1996 Apr;19(4):126-30. doi: 10.1016/s0166-2236(96)80018-x.