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低温保存的成年和幼年山羊下颌髁突移植

Cryogenically preserved adult and juvenile goat mandibular condylar transplantation.

作者信息

Bifano C A, Grellner T, Houston G, Farr S C, Ehler W J, Cissik J H, Chastain M

机构信息

Dental Services, Wilford Hall USAF Medical Center, Lackland AFB, Texas.

出版信息

Oral Surg Oral Med Oral Pathol. 1990 Mar;69(3):291-8. doi: 10.1016/0030-4220(90)90289-5.

DOI:10.1016/0030-4220(90)90289-5
PMID:2314855
Abstract

Loss of a functional temporomandibular joint (TMJ) has long been a clinical challenge in both children and adults. Although reconstruction to date has been performed with various prosthetic devices or autogenous costochondral grafts, these procedures have a potential for complications and morbidity. Our studies were performed to determine the feasibility of healing, growth, and long-term function of TMJ reconstruction techniques with cryogenically preserved mandibular allografts in the goat model. This species was chosen because the surgical anatomy and biomechanics of the goat TMJ are very similar to those of the human TMJ. The positive results of the studies and their relevance will be described.

摘要

功能性颞下颌关节(TMJ)的缺失长期以来一直是儿童和成人面临的临床挑战。尽管迄今为止已使用各种假体装置或自体肋软骨移植进行重建,但这些手术都有发生并发症和发病的可能性。我们开展这些研究的目的是确定在山羊模型中使用低温保存的下颌骨同种异体移植进行TMJ重建技术的愈合、生长及长期功能的可行性。选择该物种是因为山羊TMJ的手术解剖结构和生物力学与人TMJ非常相似。将描述研究的阳性结果及其相关性。

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