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FNA diagnosis of malignant melanoma-recurrent and metastatic disease.细针穿刺抽吸活检诊断复发性和转移性恶性黑色素瘤。
BMJ Case Rep. 2012 Nov 14;2012:bcr2012006887. doi: 10.1136/bcr-2012-006887.
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A case of amelanotic spindle-cell melanoma presenting as metastases to breast and axillary lymph node: diagnosis by FNA cytology.一例以乳腺和腋窝淋巴结转移为表现的无色素性梭形细胞黑色素瘤：经细针穿刺抽吸活检细胞学检查确诊
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An occult primary malignant melanoma in a black. Initial diagnosis by aspiration biopsy cytology of a metastasis.一名黑人患者的隐匿性原发性恶性黑色素瘤。通过转移灶的细针穿刺活检细胞学进行初步诊断。
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1
Identification of candidate tumor oncogenes by integrative molecular analysis of choroidal melanoma fine-needle aspiration biopsy specimens.通过脉络膜黑色素瘤细针穿刺活检标本的综合分子分析鉴定候选肿瘤癌基因
Arch Ophthalmol. 2010 Sep;128(9):1170-7. doi: 10.1001/archophthalmol.2010.180.
2
Ultrasound morphology criteria predict metastatic disease of the sentinel nodes in patients with melanoma.超声形态学标准预测黑色素瘤患者前哨淋巴结转移疾病。
J Clin Oncol. 2010 Feb 10;28(5):847-52. doi: 10.1200/JCO.2009.25.7428. Epub 2010 Jan 11.
3
Staging of cutaneous melanoma.皮肤黑色素瘤的分期
Ann Oncol. 2009 Aug;20 Suppl 6(Suppl 6):vi14-21. doi: 10.1093/annonc/mdp256.
4
Traditional urinary cytology and tyrosinase RT-PCR in metastatic melanoma patients: correlation with clinical status.转移性黑色素瘤患者的传统尿液细胞学检查和酪氨酸酶逆转录聚合酶链反应：与临床状态的相关性
J Clin Pathol. 2008 Feb;61(2):179-83. doi: 10.1136/jcp.2007.049577. Epub 2007 Aug 3.
5
The heterogeneous distribution of monosomy 3 in uveal melanomas: implications for prognostication based on fine-needle aspiration biopsies.葡萄膜黑色素瘤中3号染色体单体的异质性分布：基于细针穿刺活检对预后的影响
Arch Pathol Lab Med. 2007 Jan;131(1):91-6. doi: 10.5858/2007-131-91-THDOMI.
6
HSP-70, C-myc and HLA-DR expression in patients with cutaneous malignant melanoma metastatic in lymph nodes.HSP-70、C-myc及HLA-DR在皮肤恶性黑色素瘤淋巴结转移患者中的表达
Anticancer Res. 2006 Sep-Oct;26(5A):3551-4.
7
Ultrasound-guided fine needle aspiration cytology prior to sentinel lymph node biopsy in melanoma patients.黑色素瘤患者前哨淋巴结活检前的超声引导下细针穿刺细胞学检查
Ann Surg Oncol. 2006 Dec;13(12):1682-9. doi: 10.1245/s10434-006-9046-4.
8
Ultrasonography and fine-needle aspiration cytology in the preoperative evaluation of melanoma patients eligible for sentinel node biopsy.超声检查和细针穿刺细胞学检查在适合前哨淋巴结活检的黑色素瘤患者术前评估中的应用
Ann Surg Oncol. 2006 Nov;13(11):1511-6. doi: 10.1245/s10434-006-9106-9. Epub 2006 Sep 29.
9
A rare case of primary malignant melanoma of the scrotum diagnosed by fine-needle aspiration.一例通过细针穿刺确诊的阴囊原发性恶性黑色素瘤罕见病例。
Diagn Cytopathol. 2004 Dec;31(6):413-6. doi: 10.1002/dc.20153.
10
Novel tyramide-based tyrosinase assay for the detection of melanoma cells in cytological preparations.用于在细胞学制剂中检测黑色素瘤细胞的新型基于酪胺的酪氨酸酶测定法。
Diagn Cytopathol. 2004 Jul;31(1):33-7. doi: 10.1002/dc.20051.

细针穿刺抽吸活检诊断复发性和转移性恶性黑色素瘤。

FNA diagnosis of malignant melanoma-recurrent and metastatic disease.

作者信息

Alam Kiran, Jain Anshu, Aziz Meher, Misra Aroonima

机构信息

Department of Pathology, J N Medical College, Aligarh, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2012 Nov 14;2012:bcr2012006887. doi: 10.1136/bcr-2012-006887.

DOI:10.1136/bcr-2012-006887
PMID:23152178
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4544183/
Abstract

We present a case of a 60-year-old woman with multiple right axillary swellings. Patient had a history of lump with pigmentation over back for which she was operated upon. There was also a nodule over resected scar on back. A final diagnosis of malignant melanoma (recurrent and metastatic to axillary lymph nodes) was rendered with the help of fine-needle aspiration cytology (FNAC). Malignant melanomas are the most lethal of cancers of the skin and are notorious for the great variability of cytological presentation. We discuss the role of FNAC in early diagnosis and prognostication of recurrent and metastatic disease.

摘要

我们报告一例60岁女性，其右侧腋窝出现多处肿物。患者背部曾有伴有色素沉着的肿块并接受了手术治疗。背部切除瘢痕处也有一个结节。借助细针穿刺细胞学检查（FNAC）最终诊断为恶性黑色素瘤（复发并转移至腋窝淋巴结）。恶性黑色素瘤是皮肤癌中致死率最高的，其细胞学表现差异极大，因而声名狼藉。我们讨论了FNAC在复发性和转移性疾病的早期诊断及预后判断中的作用。