Moore S G, Dawson K L
Department of Radiology, Stanford University School of Medicine, CA 94305-5105.
Radiology. 1990 Apr;175(1):219-23. doi: 10.1148/radiology.175.1.2315484.
T1-weighted magnetic resonance (MR) images of the femur in 77 subjects, aged 1 month to 24 years, were retrospectively analyzed for the distribution and appearance of red and yellow marrow. The subjects were divided into six age groups, and the signal intensity and degree of mottling of marrow in the proximal epiphysis, proximal metaphysis, diaphysis, distal metaphysis, and distal epiphysis were observed and assigned a grade. Bone marrow with low or intermediate to slightly increased signal intensity was considered red marrow, while bone marrow with increased signal intensity was considered fatty marrow. An orderly progression of red to yellow marrow conversion in the femur was appreciated first in the diaphysis (ages 1-10 years) and then in the distal metaphysis (ages 10-20 years), with an adult pattern seen by age 24 years. The MR spectrum of red and yellow marrow differs from the existing macroscopic anatomical data because MR imaging is apparently more sensitive to the presence of microscopic fat in bone marrow.
对77名年龄在1个月至24岁之间的受试者的股骨进行了T1加权磁共振（MR）图像回顾性分析，以观察红骨髓和黄骨髓的分布及表现。将受试者分为六个年龄组，观察股骨近端骨骺、近端干骺端、骨干、远端干骺端和远端骨骺骨髓的信号强度及斑驳程度，并进行分级。信号强度低或中等至轻度增加的骨髓被视为红骨髓，而信号强度增加的骨髓被视为脂肪骨髓。股骨中红骨髓向黄骨髓的转化首先在骨干（1 - 10岁）出现，然后在远端干骺端（10 - 20岁）出现，到24岁时呈现成人模式。红骨髓和黄骨髓的MR光谱与现有的宏观解剖数据不同，因为MR成像对骨髓中微观脂肪的存在显然更敏感。
