Department of Women's and Children's Health, Uppsala University, Akademiska Hospital, Uppsala, Sweden.
Acta Obstet Gynecol Scand. 2013 Feb;92(2):178-84. doi: 10.1111/aogs.12041. Epub 2012 Dec 14.
To investigate a possible association between postpartum depression and premenstrual symptoms.
Population-based cohort.
University Hospital, Sweden.
During one year, May 2006 to June 2007, all delivering women in the hospital were asked to participate.
The participating women answered three questionnaires, at five days, six weeks and six months postpartum, containing the Edinburgh Postnatal Depression Scale (EPDS) and questions assessing previous premenstrual symptoms, medical history and life style.
The woman's self-reported depressive case/control status, women with 12 or more points on the EPDS being considered as cases.
Among the 2318 participating women, 7.1% had a history of premenstrual syndrome and 2.9% a history of premenstrual dysphoric disorder. Previous premenstrual syndrome/premenstrual dysphoric disorder was associated with self-reported postpartum depression at five days, six weeks and six months postpartum. After stratification for parity, the associations remained significant solely among multiparas.
There appears to be an association between a history of premenstrual symptoms and development of self-reported postpartum depression. Parity was identified as effect modifier. This finding is clinically important for health care professionals working in maternity care.
探讨产后抑郁症与经前症状之间可能存在的关联。
基于人群的队列研究。
瑞典大学医院。
在 2006 年 5 月至 2007 年 6 月的一年期间，医院所有分娩的女性都被邀请参与。
参与的女性在产后 5 天、6 周和 6 个月时回答了三个问卷，其中包含爱丁堡产后抑郁量表（EPDS）和评估经前症状、既往病史和生活方式的问题。
女性自我报告的抑郁病例/对照组状态，EPDS 得分为 12 分或以上的女性被认为是病例。
在 2318 名参与的女性中，7.1%有经前综合征病史，2.9%有经前烦躁障碍病史。既往经前综合征/经前烦躁障碍与产后 5 天、6 周和 6 个月时的自我报告产后抑郁症相关。按产次分层后，这种关联仅在多产妇中仍然显著。
经前症状史与自我报告的产后抑郁症发展之间似乎存在关联。产次被确定为效应修饰剂。这一发现对在产科保健工作的医疗保健专业人员具有重要的临床意义。
