Institute of Organic Chemistry, University of Innsbruck, Center for Chemistry and Biomedicine, Austria.
Angew Chem Int Ed Engl. 2012 Dec 21;51(52):13080-4. doi: 10.1002/anie.201207128. Epub 2012 Nov 19.
Fluorishing: the Togni reagent allows efficient synthetic access to fluorine-labeled RNA molecules. These are in turn highly useful for NMR spectroscopic analyses of secondary and tertiary structures, RNA-protein interactions, and functionality of riboswitch modules.
托尼试剂允许高效合成氟标记的 RNA 分子。这些 RNA 分子对于 NMR 光谱分析二级和三级结构、RNA-蛋白质相互作用以及核酶模块的功能非常有用。