Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, South Korea.
Angiology. 2013 May;64(4):314-20. doi: 10.1177/0003319712464814. Epub 2012 Nov 15.
We evaluated the sensitivity and specificity of ankle-brachial index (ABI), photoplethysmography (PPG), and continuous-wave Doppler ultrasound (CWD) in the detection of anatomically stenotic peripheral arterial disease (PAD).
Ninety-seven patients (194 legs) patients who had coincidentally undergone computed tomography angiography (CTA), ABI, PPG, and CWD for the evaluation of PAD were retrospectively reviewed. Sensitivity and specificity were measured.
Among 194 legs, 163 (84%) legs had stenotic PAD on CTA. Overall sensitivity of ABI, PPG, and CWD was 69.3%, 81.6%, and 90.8% and specificity was 96.8%, 77.4%, and 64.5%, respectively. Ankle-brachial index showed a statistically significantly decreased sensitivity (14.8%) for below trifurcation level stenosis compared with CWD (92%) and PPG (67%). The sensitivity of ABI was also significantly decreased in single level and moderate stenosis (45.1% and 42.1%, respectively). In contrast, the sensitivity of CWD and PPG was not significantly decreased.
The ABI showed significantly decreased sensitivity especially in stenosis below the trifurcation level. Both PPG and CWD were complementary to ABI in these groups of patients.
我们评估了踝臂指数（ABI）、光体积描记法（PPG）和连续波多普勒超声（CWD）在检测解剖狭窄性外周动脉疾病（PAD）中的敏感性和特异性。
回顾性分析了 97 例（194 条腿）同时接受计算机断层血管造影（CTA）、ABI、PPG 和 CWD 检查以评估 PAD 的患者。测量了敏感性和特异性。
在 194 条腿中，163 条（84%）腿的 CTA 显示有狭窄性 PAD。ABI、PPG 和 CWD 的总体敏感性分别为 69.3%、81.6%和 90.8%，特异性分别为 96.8%、77.4%和 64.5%。ABI 对分叉以下水平狭窄的敏感性（14.8%）明显低于 CWD（92%）和 PPG（67%）。ABI 在单水平和中度狭窄（分别为 45.1%和 42.1%）中的敏感性也明显降低。相比之下，CWD 和 PPG 的敏感性并未明显降低。
ABI 在下三分叉以下狭窄的情况下敏感性明显降低。在这些患者群体中，PPG 和 CWD 均可以补充 ABI 的不足。
