平均血小板体积能否成为门静脉血栓形成的新危险因素？
Can mean platelet volume be a new risk factor in portal venous thrombosis?
机构信息
Department of General Surgery, Dicle University, Diyarbakır, Turkey.
出版信息
Clin Appl Thromb Hemost. 2013 Jul-Aug;19(4):433-6. doi: 10.1177/1076029612464903. Epub 2012 Nov 15.
BACKGROUND
The aim of this study was to discuss the possibility of mean platelet volume (MPV) being a new risk factor in the etiology of portal venous thrombosis (PVT).
METHODS
Study participants were categorized into 2 different groups: group I, control group (n = 35) and group II, PVT group (n = 34). Demographic data and MPV values were recorded retrospectively.
RESULTS
No differences were determined between the 2 groups regarding hypertension, diabetes mellitus, and smoking (P > .05). The average hemoglobin levels were 10.8 ± 2.1 in group II and 14.0 ± 1.7 in group I (P < .001). Although the MPV levels of group II patients were 8.2 ± 0.52, the average level in group I was determined as 7.8 ± 0.62 (P = .012). In the performed receiver-operating characteristic (ROC) analysis, the cutoff value for patients with PVT for MPV was determined as 7.9 (area under curve: 0.674), sensitivity as 70.6%, and specificity as 65.7% (P = .013).
CONCLUSION
The current study shows that MPV is significantly higher in patients with PVT than in the control group.
背景
本研究旨在探讨平均血小板体积（MPV）是否可能成为门静脉血栓形成（PVT）病因学中的一个新的危险因素。
方法
研究参与者被分为两组：I 组，对照组（n=35）和 II 组，PVT 组（n=34）。回顾性记录人口统计学数据和 MPV 值。
结果
两组在高血压、糖尿病和吸烟方面无差异（P＞.05）。II 组的平均血红蛋白水平为 10.8±2.1，I 组为 14.0±1.7（P＜.001）。虽然 II 组患者的 MPV 水平为 8.2±0.52，但 I 组的平均水平为 7.8±0.62（P=.012）。在进行的接收者操作特征（ROC）分析中，PVT 患者的 MPV 截断值为 7.9（曲线下面积：0.674），敏感性为 70.6%，特异性为 65.7%（P=.013）。
结论
本研究表明，PVT 患者的 MPV 明显高于对照组。
Zotero 插件