Tanaka Satoru, Sato Nayuko, Fujioka Hiroya, Takahashi Yuko, Kimura Kosei, Iwamoto Mitsuhiko, Uchiyama Kazuhisa
Section of Breast and Endocrine Surgery, Department of General and Gastroenterological Surgery, Osaka Medical College, Takatsuki, Osaka 569-8686, Japan.
Oncol Lett. 2012 Nov;4(5):889-892. doi: 10.3892/ol.2012.871. Epub 2012 Aug 20.
Metastatic breast tumors are rare; however, malignant melanoma is one of the primary tumors most commonly reported to metastasize to the breast. Among these, the primary tumors typically associated with metastasis to the breast are cutaneous melanomas. We present, herein, a very rare case of solitary metastasis to the left breast from malignant melanoma of the nasal cavity, which represents less than 1% of all malignant melanomas. The patient, a 78-year-old woman, was treated using a combination of surgery and radiotherapy. In the absence of therapeutic efficacy, disease progression was very rapid. No previous studies have described malignant melanoma of the nasal cavity with solitary breast metastasis. This case report aims to increase awareness of the need to establish treatment strategies based on an understanding of the etiology and pathophysiology.
转移性乳腺肿瘤较为罕见;然而,恶性黑色素瘤是最常被报道转移至乳腺的原发性肿瘤之一。其中,通常与乳腺转移相关的原发性肿瘤是皮肤黑色素瘤。在此,我们报告一例极为罕见的鼻腔恶性黑色素瘤孤立性转移至左乳的病例,此类病例在所有恶性黑色素瘤中占比不到1%。该患者为一名78岁女性,接受了手术和放疗联合治疗。在缺乏治疗效果的情况下,疾病进展非常迅速。此前尚无研究描述过鼻腔恶性黑色素瘤伴孤立性乳腺转移的情况。本病例报告旨在提高人们对基于病因学和病理生理学认识制定治疗策略必要性的认识。