Department of Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Ocul Immunol Inflamm. 2012 Dec;20(6):460-3. doi: 10.3109/09273948.2012.723108. Epub 2012 Nov 19.
To present a case report in which fundus autofluorescence (FAF) helped to diagnose and monitor the clinical course of a patient diagnosed with punctate inner choroidopathy (PIC).
Retrospective chart review of patient data.
FAF showed multiple hypoautofluorescent spots in the posterior pole.It also showed an area of hypoautofluorescence surrounded by a ring of hyperautofluorescence, which corresponded to a larger lesion seen clinically. As the disease became inactive, the number of hypoautofluorescent spots decreased. The rim of hyperautofluorescence surrounding the macular lesion became attenuated.Persistent hypofluorescent areas grew in size.
FAF is a useful imaging modality to better visualize and delineate the extent of damaged retinal pigment epithelium (RPE) in PIC. FAF also helps the clinician to assess the resolution of the disease by the appearance of the RPE.
报告一例病例,眼底自发荧光(FAF)有助于诊断和监测点状内层脉络膜病变(PIC)患者的临床病程。
回顾性分析患者数据。
FAF 在后极部显示多个低自发荧光点。它还显示出一个低自发荧光区域,周围环绕着一个高自发荧光环,与临床上看到的较大病变相对应。随着疾病的静止,低自发荧光点的数量减少。黄斑病变周围的高自发荧光环变细。持续的低荧光区域增大。
FAF 是一种有用的成像方式,可以更好地观察和描绘 PIC 中视网膜色素上皮(RPE)损伤的范围。FAF 还可以通过 RPE 的外观帮助临床医生评估疾病的缓解情况。