Wang Guan-Feng, Zou Xiu-Lan
Department of Ophthalmology, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, Guangdong Province, China ; Jinan University, Guangzhou 510630, Guangdong Province, China.
Int J Ophthalmol. 2012;5(5):609-13. doi: 10.3980/j.issn.2222-3959.2012.05.13. Epub 2012 Oct 18.
Wet age-related macular degeneration which incidence increases year by year is a blinding eye disease, but current clinical methods of treatment on this disease are limited and the outcome is not ideal. Recent studies have found abnormally high expression of tissue factors which are targets for the treatment of wet age-related macular degeneration to achieve a certain effect in the choroidal neovascularization. Related literatures are reviewed as following.
湿性年龄相关性黄斑变性是一种致盲性眼病,其发病率逐年上升,但目前针对该疾病的临床治疗方法有限,治疗效果并不理想。最近的研究发现,组织因子表达异常增高,而组织因子是治疗湿性年龄相关性黄斑变性的靶点,在脉络膜新生血管形成方面可取得一定疗效。现将相关文献综述如下。