Kauhanen Susanna, Peltoniemi Hilkka
HYKS, Jorvin Sairaala, plastiikkakirurgian klinikka.
Duodecim. 2012;128(20):2074-84.
Free fat transfer or lipofilling is a procedure quickly increasing in popularity. Free fat transfer offers treatment for soft tissue defects caused by trauma or cancer, congenital anomalies, painful scars, irradiation injuries and aesthetic indications. The advantages compared to, e.g., traditional flap reconstructions includes surgical easiness, minor donor-site morbidity, easy access, hardly no scars, quick recovery and avoidance of foreign bodies such as implants. The regenerative potential of free fat transfer is due to abundant adipose derived mesenchymal stem cells (ADSC). These cells are under extremely active investigation and have rapidly led to clinical trials and treatment modalities in combination with tissue engineering. Free fat transfer nowadays offers hope to patients that formerly could not be helped with surgical intervention.
游离脂肪移植或脂肪填充是一种迅速流行起来的手术。游离脂肪移植可用于治疗由创伤、癌症、先天性畸形、疼痛性瘢痕、放射性损伤和美学指征引起的软组织缺损。与传统皮瓣重建等方法相比，其优点包括手术操作简便、供区并发症少、易于实施、几乎不留瘢痕、恢复快以及避免使用植入物等异物。游离脂肪移植的再生潜力源于丰富的脂肪源性间充质干细胞（ADSC）。这些细胞正处于极为活跃的研究中，并迅速促成了结合组织工程的临床试验和治疗方式。如今，游离脂肪移植为那些以前无法通过手术干预得到帮助的患者带来了希望。
