Yu Dingqun, Tang Haoru, Zhang Yong, Luo Ya, Liu Zejing
College of Horticulture, Sichuan Agricultural University, Ya'an, China.
Sheng Wu Gong Cheng Xue Bao. 2012 Jul;28(7):800-12.
Glucose-6-phosphate dehydrogenase (G6PDH) catalyzes the first and rate-limiting step of the oxidative pentose phosphate pathway, existing in both cytosolic and plastidic compartments of higher plants. Its main function is to provide reducing power (NADPH) and pentose phosphates for reductive biosynthesis and maintenance of the redox state of the cell. In addition, the expression of this enzyme is related to different biotic and abiotic stresses. In this review, we analyzed the isoenzyme, regulation and biological function of G6PDH. Meanwhile, we summarized the progress work of G6PDH involved in stress resistance, gene cloning, enzyme-deficiency and cluster analysis. Problems should be solved were also discussed.
葡萄糖-6-磷酸脱氢酶（G6PDH）催化氧化戊糖磷酸途径的第一步也是限速步骤，存在于高等植物的细胞质和质体区室中。其主要功能是为还原性生物合成和维持细胞的氧化还原状态提供还原力（NADPH）和戊糖磷酸。此外，该酶的表达与不同的生物和非生物胁迫有关。在本综述中，我们分析了G6PDH的同工酶、调控和生物学功能。同时，我们总结了G6PDH在抗逆性、基因克隆、酶缺陷和聚类分析方面的研究进展。还讨论了有待解决的问题。
