Mantri Surag, Macaraeg Chris, Shetty Sujith, Aljuri Nikolai, Freitag Lutz, Herth Felix, Eberhardt Ralf, Ernst Armin
*Pulmonx, Inc, Palo Alto, CA †Department of Pneumology and Critical Care Medicine, Thoraxklinik, University of Heidelberg, Germany ‡Department of Interventional Pulmonology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.
J Bronchology Interv Pulmonol. 2009 Apr;16(2):141-4. doi: 10.1097/LBR.0b013e3181a40a3e.
Interest in assessment of collateral flow measurement has resurfaced with the advent of endoscopic lung volume reduction studies, namely valve technologies (eg Emphasys EBV), that achieve volume reduction through lobar isolation. It is currently thought that collateral ventilation could be a contributing factor for endoscopic lung volume reduction failures, as isolated lobes can "backfill" through these channels. In an attempt to quantify collateral ventilation, the Chartis System has been developed by Pulmonx, Inc. to measure pressure and flow, and calculate resistance to airflow through collateral channels in isolated lung compartments.
随着内镜下肺减容研究的出现，即通过叶隔离实现肺减容的瓣膜技术（如Emphasys EBV），对侧支血流测量评估的兴趣再度兴起。目前认为，侧支通气可能是内镜下肺减容失败的一个促成因素，因为孤立的肺叶可以通过这些通道“回充”。为了量化侧支通气，Pulmonx公司开发了Chartis系统，用于测量压力和流量，并计算通过孤立肺段侧支通道的气流阻力。
