Henry Ford Hospital, Detroit, MI, USA.
Int J Dermatol. 2012 Dec;51(12):1419-26. doi: 10.1111/j.1365-4632.2012.05545.x.
We report a case of a 2-week-old white female who presented with large stellate atrophic skin defects on bilateral thighs and knees at birth. The pregnancy was complicated by the death of monozygotic twin at the 16th week of gestation. This represents aplasia cutis congenita with fetus papyraceus. This rare condition is defined as the congenital skin defect and intrauterine death of fetus with or without a stillborn fetus pressed flat by the growing twin (fetus papyraceus) at delivery time. Aplasia cutis congenita coexisting with fetus papyraceus has a distinctive and reproducible distribution pattern of bilateral symmetrical truncal, buttock, and thigh lesions related to fetal death during the late first to early second trimester. There are at least 44 reported cases of this disorder in the English literature. We discuss our case and review the literature.
我们报告了一例 2 周龄女婴，出生时双侧大腿和膝盖呈现星状萎缩性皮肤缺陷。该妊娠合并 16 孕周单卵双胎胎儿死亡。这代表了先天性皮肤缺陷和伴或不伴木乃伊化胎儿的宫内胎儿死亡，这些胎儿在分娩时被生长的双胞胎（纸样胎儿）压平。先天性皮肤缺陷伴纸样胎儿的罕见疾病具有独特且可重复的双侧对称性躯干、臀部和大腿损伤分布模式，与妊娠中期晚期至早期第二期的胎儿死亡有关。在英文文献中至少有 44 例这种疾病的报道。我们讨论了我们的病例并回顾了文献。
