Laasonen L, Gripenberg M, Leskinen R, Skrifvars B, Edgren J
IVth Department of Medicine, Helsinki University Central Hospital, Finland.
Ann Rheum Dis. 1990 Feb;49(2):118-20. doi: 10.1136/ard.49.2.118.
Clinical and serological findings of 16 patients with systemic lupus erythematosus (SLE) who had progressive cystic bone lesions were compared with a control group of 19 patients with SLE without radiological evidence of bone cysts. Central nervous system manifestations, synovitis, and other radiologically observed skeletal abnormalities were more prevalent in the patients with cysts than in the control group. Higher concentrations of C reactive protein, and a greater incidence of rheumatoid factor positivity were seen in the patients with cysts than in the control patients, but no other serological differences were found. It is suggested that patients with SLE with progressive cystic lesions form a subgroup of the syndrome characterised by an increased acute phase reaction.
对16例患有进行性囊性骨病变的系统性红斑狼疮（SLE）患者的临床和血清学检查结果，与19例无骨囊肿放射学证据的SLE患者对照组进行了比较。囊肿患者的中枢神经系统表现、滑膜炎及其他放射学观察到的骨骼异常，比对照组更为普遍。囊肿患者的C反应蛋白浓度更高，类风湿因子阳性发生率也高于对照患者，但未发现其他血清学差异。提示患有进行性囊性病变的SLE患者构成了该综合征的一个亚组，其特征为急性期反应增强。
