Tan Ava Grace, Tay Wan Ting, Mitchell Paul, Sandar Mya, Aung Tin, Saw Seang-Mei, Wang Jie Jin, Wong Tien Yin
Centre for Vision Research, Department of Ophthalmology and Westmead Millennium Institute, University of Sydney, Sydney, Australia.
Ophthalmic Epidemiol. 2012 Dec;19(6):380-7. doi: 10.3109/09286586.2012.733479.
To describe the prevalence of lens opacities and cataract surgery in an older Malay population in Singapore.
The Singapore Malay Eye Study is a population-based cross-sectional study of 3280 (78.7% response rate) Malay adults aged 40-80 years. Participants underwent a standardized clinical eye examination. Digital slit-lamp and retroillumination photographs were taken of both eyes of each participant and graded for age-related nuclear, cortical and posterior subcapsular (PSC) cataract, following the Wisconsin Cataract Grading System. Other lens opacities, including retrodots and vacuoles, were also graded. Information on medical and lifestyle factors was collected using questionnaires. The study sample was directly age-standardized to the Malay population in Singapore using the 2000 Singapore population census.
A total of 3054 (97.7%) and 3113 (99.6%) participants had gradable Topcon slit lamp and Neitz photographs, respectively. The overall age-adjusted prevalence of any cataract was 29.1%, and that of nuclear, cortical and PSC cataract were 12.9% (95% confidence interval, CI, 11.2-13.1%), 21.2% (95% CI 19.8-22.7%) and 9.7% (95% CI 8.8-10.8%), respectively. Age-adjusted prevalence of cataract surgery was 4.7% (95% CI 4.2-5.4%). Prevalence of all three cataract types and cataract surgery increased with age. Age-adjusted prevalence for retrodots and vacuoles were 19.7% (95% CI 18.3-21.1%) and 64.3% (95% CI 61.1-67.6%), respectively. Retrodots were found to be associated with prevalence of all three cataract types, while vacuoles were associated with cortical and PSC cataract prevalence.
Lens opacities were common in this urban Malay population. Retrodots and vacuoles were found to be associated with age-related cataract.
描述新加坡老年马来人群中晶状体混浊和白内障手术的患病率。
新加坡马来眼研究是一项基于人群的横断面研究，研究对象为3280名年龄在40 - 80岁的马来成年人（应答率为78.7%）。参与者接受了标准化的临床眼科检查。对每位参与者的双眼进行数码裂隙灯和后照法摄影，并按照威斯康星白内障分级系统对年龄相关性核性、皮质性和后囊下（PSC）白内障进行分级。其他晶状体混浊，包括后点状混浊和空泡，也进行了分级。使用问卷收集有关医疗和生活方式因素的信息。研究样本根据2000年新加坡人口普查数据直接对新加坡马来人群进行年龄标准化。
分别有3054名（97.7%）和3113名（99.6%）参与者获得了可分级的拓普康裂隙灯照片和尼兹照片。任何白内障的总体年龄调整患病率为29.1%，核性、皮质性和PSC白内障的患病率分别为12.9%（95%置信区间，CI，11.2 - 13.1%）、21.2%（95%CI 19.8 - 22.7%）和9.7%（95%CI 8.8 - 10.8%）。白内障手术的年龄调整患病率为4.7%（95%CI 4.2 - 5.4%）。所有三种白内障类型和白内障手术的患病率均随年龄增长而增加。后点状混浊和空泡的年龄调整患病率分别为19.7%（95%CI 18.3 - 21.1%）和64.3%（95%CI 61.1 - 67.6%）。发现后点状混浊与所有三种白内障类型的患病率相关，而空泡与皮质性和PSC白内障的患病率相关。
晶状体混浊在这个城市马来人群中很常见。发现后点状混浊和空泡与年龄相关性白内障有关。
Zotero 插件