Varma Rohit, Sun Jie, Torres Mina, Wu Shuang, Hsu Chunyi, Azen Stanley Paul, McKean-Cowdin Roberta
USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, California, United States.
Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, California, United States.
Invest Ophthalmol Vis Sci. 2016 Dec 1;57(15):6692-6699. doi: 10.1167/iovs.16-20517.
We determined the age- and sex-specific prevalence of posterior subcapsular (PSC), nuclear, cortical, and mixed lens opacities in a population-based sample of Chinese-American adults.
A population-based sample of Chinese-Americans 50 years and older, from 10 census tracts in Monterey Park, CA, USA, underwent a detailed interview and a comprehensive clinical examination that included assessment of different types of lens opacities by the slit-lamp-based Lens Opacities Classification System II (LOCS II). All lens changes (including pseudophakia/aphakia), PSC, nuclear, and/or cortical opacities, were evaluated and graded.
Of the 5782 eligible subjects, 4582 (79.2%) Chinese Americans aged 50 years and older completed a comprehensive eye examination. Of the participants with LOCS II grading (n = 4234/4582, 92%), 3.0% had PSC opacities, 38.1% had nuclear opacities, and 23.4% had cortical opacities. The prevalence of all lens changes was 48.0% for all age groups and was higher by 10-year increasing age groups (P < 0.0001). The prevalence of visual impairment in the better-seeing eye with cortical only, nuclear only, PSC only, and mixed opacities was 3.9%, 5.0%, 14.3%, and 9.4%, respectively. A total of 454 (9.9%) individuals had undergone cataract extraction in at least one eye.
Chinese Americans have a high prevalence of visual impairment associated with lens opacities, and a high prevalence of nuclear opacities. Public health policies and programs designed to improve cataract detection and treatment could help reduce the burden of visual impairment in Chinese Americans.
我们在一个以社区为基础的华裔美国成年人样本中，确定了后囊下（PSC）、核性、皮质性及混合性晶状体混浊的年龄和性别特异性患病率。
从美国加利福尼亚州蒙特利公园市10个人口普查区中选取年龄在50岁及以上的华裔美国人作为社区样本，对其进行详细访谈和全面的临床检查，包括使用基于裂隙灯的晶状体混浊分类系统II（LOCS II）评估不同类型的晶状体混浊。对所有晶状体变化（包括人工晶状体/无晶状体）、PSC、核性和/或皮质性混浊进行评估和分级。
在5782名符合条件的受试者中，4582名（79.2%）年龄在50岁及以上的华裔美国人完成了全面的眼部检查。在进行LOCS II分级的参与者中（n = 4234/4582，92%），3.0%患有PSC混浊，38.1%患有核性混浊，23.4%患有皮质性混浊。所有年龄组中所有晶状体变化的患病率为48.0%，且随年龄每增加10岁患病率升高（P < 0.0001）。仅皮质性、仅核性、仅PSC性和混合性混浊的较好眼视力损害患病率分别为3.9%、5.0%、14.3%和9.4%。共有454名（9.9%）个体至少一只眼睛接受了白内障摘除术。
华裔美国人中与晶状体混浊相关的视力损害患病率较高，核性混浊患病率也较高。旨在改善白内障检测和治疗的公共卫生政策和项目有助于减轻华裔美国人视力损害的负担。
