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青少年欺凌、大麻使用与早期精神病性体验:一项纵向的一般人群研究。

Adolescent bullying, cannabis use and emerging psychotic experiences: a longitudinal general population study.

机构信息

Addictions Department, Institute of Psychiatry, King's College London, UK.

出版信息

Psychol Med. 2013 May;43(5):1033-44. doi: 10.1017/S003329171200205X. Epub 2012 Sep 7.

Abstract

BACKGROUND

Using longitudinal and prospective measures of psychotic experiences during adolescence, we assessed the risk of developing psychosis in three groups showing low, increasing and elevated psychotic experiences associated with bullying by peers and cannabis use in a UK sample of adolescents. Method Data were collected by self-report from 1098 adolescents (mean age 13.6 years; 60.9% boys) at five separate time points, equally separated by 6 months, across a 24-month period. General growth mixture modelling identified three distinct trajectories of adolescents reporting psychotic experiences: elevated, increasing and low.

RESULTS

Controlling for cannabis use, bullying by peers significantly predicted change in psychotic experiences between Time 2 and Time 5 in adolescents belonging to the increasing group. No effect was found for the elevated or low groups. Controlling for bullying, an earlier age of cannabis use and cannabis use more than twice significantly predicted change in psychotic experiences in adolescents belonging to the increasing group. Cannabis use at any age was significantly associated with subsequent change in psychotic experiences in the low group. Reverse causal associations were examined and there was no evidence for psychotic experiences at Time 1 predicting a subsequent change in cannabis use between Times 2 and 5 in any trajectory group.

CONCLUSIONS

Bullying by peers and cannabis use are associated with adolescents' reports of increasing psychotic experiences over time. Further research into the longitudinal development of psychosis in adolescence and the associated risk factors would allow for early intervention programmes to be targeted more precisely.

摘要

背景

本研究使用青少年期精神病性体验的纵向和前瞻性测量方法,评估了三组青少年的精神病发病风险,这三组青少年分别与同伴欺凌和大麻使用相关的低度、递增和升高的精神病性体验有关,该研究样本来自英国。

方法

本研究数据由 1098 名青少年(平均年龄 13.6 岁;60.9%为男性)在 24 个月的时间内,通过自我报告,在五个时间点收集,每个时间点之间的间隔相等,为 6 个月。广义增长混合模型确定了报告精神病性体验的青少年存在三种不同轨迹:升高、递增和低度。

结果

在控制大麻使用的情况下,同伴欺凌显著预测了属于递增组的青少年在第 2 次和第 5 次时间点之间精神病性体验的变化。对于升高组和低度组,没有发现这种影响。在控制欺凌的情况下,较早的大麻使用年龄和大麻使用次数超过两次显著预测了属于递增组的青少年精神病性体验的变化。在任何年龄使用大麻都与低度组随后的精神病性体验变化显著相关。

结论

同伴欺凌和大麻使用与青少年随时间报告的精神病性体验的增加有关。进一步研究青少年期精神病的纵向发展及其相关风险因素,将使早期干预计划能够更准确地针对目标。

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