Department of Mathematics and Statistics, University of Vermont, Burlington, Vt 05405, USA.
J Occup Environ Med. 2012 Dec;54(12):1447-52. doi: 10.1097/JOM.0b013e3182783f27.
Theories of stress-induced metabolic syndrome predict that job strain would increase risk. Few studies have evaluated this association.
To evaluate the association between job strain and the risk of metabolic syndrome.
We investigated associations between job strain and incident metabolic syndrome adjusted for sociodemographic factors, health behaviors, and depressive symptoms over 5 years among 2966 black and white men and women in the Coronary Artery Risk Development in Young Adults study. Job strain was categorized by Karasek's model: high demands/low control; high demands/high control; low demands/low control; and low demands/high control.
Compared with persons in low-strain jobs, men in active jobs (adjusted hazards ratio, 2.7; 95% confidence interval, 1.5 to 4.9) and women in high strain jobs (adjusted hazards ratio, 2.2; 95% confidence interval, 1.0 to 4.6) had significantly increased risk of metabolic syndrome.
Job strain may be a modifiable risk factor for metabolic syndrome and subsequent cardiovascular disease.
应激导致的代谢综合征理论预测工作压力会增加患病风险。但鲜有研究对此进行评估。
评估工作压力与代谢综合征风险之间的关系。
我们对冠状动脉风险发展中的年轻成年人研究中的 2966 名黑人和白人男性和女性进行了为期 5 年的研究，将社会人口因素、健康行为和抑郁症状等因素进行调整后，研究了工作压力与代谢综合征之间的关联。工作压力采用 Karasek 模型进行分类：高要求/低控制；高要求/高控制；低要求/低控制；低要求/高控制。
与低压力工作的人相比，男性从事积极工作（调整后的危险比，2.7；95%置信区间，1.5 至 4.9）和女性从事高压力工作（调整后的危险比，2.2；95%置信区间，1.0 至 4.6）的人患代谢综合征的风险显著增加。
工作压力可能是代谢综合征和随后心血管疾病的一个可改变的危险因素。
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