Department of Psychiatry, McGill University, Montreal, QC, Canada; Douglas Mental Health University Institute, Montreal, QC, Canada.
Department of Psychiatry, McGill University, Montreal, QC, Canada; Douglas Mental Health University Institute, Montreal, QC, Canada; UCD School of Psychology, University College Dublin, Ireland.
J Psychosom Res. 2020 Dec;139:110268. doi: 10.1016/j.jpsychores.2020.110268. Epub 2020 Oct 6.
Job strain (high psychological demands and low decision control) is associated with cardiovascular diseases, however it remains unclear if the associations are explained by depressive symptoms, and whether there are sex differences. The objective of the present study was to evaluate the association between job strain and heart diseases in a middle-aged population-based cohort.
Baseline data were from CARTaGENE, a community survey of adults aged 40-60 years in Quebec, Canada. Incidence of heart diseases was examined in 8073 individuals by linking survey data with administrative data. Cox regression models were used to examine the association between job strain and heart disease, adjusting for sociodemographic characteristics, behavioral and clinical factors, and depressive symptoms.
In total, 557 (6.9%) participants developed heart diseases over an average follow-up of 6.6 years. Job strain was associated with an increased risk of heart diseases in women (adjusted HR = 1.63, 95% CI 1.02-2.64) after controlling for depressive symptoms, behavioral and clinical factors. There was no overall association between job strain and heart diseases in men (adjusted HR = 0.96, 95% CI 0.62-1.49); an association was observed only in men aged 50 years and older. Incidence of heart diseases and high job strain was highest in those with labour jobs, and lowest in those with professional jobs.
Job strain was associated with an increased risk of heart diseases in middle-aged women and in men aged 50 years and older. This association was not accounted for by depressive symptoms or sociodemographic, clinical, and behavioral factors.
工作压力（高心理需求和低决策控制）与心血管疾病有关，但目前尚不清楚这些关联是否可以用抑郁症状来解释，以及是否存在性别差异。本研究的目的是评估中年人群中工作压力与心脏病之间的关系。
本研究的数据来自 CARTaGENE，这是加拿大魁北克省一项针对 40-60 岁成年人的社区调查。通过将调查数据与行政数据相联系，对 8073 名个体的心脏病发病率进行了评估。使用 Cox 回归模型来检验工作压力与心脏病之间的关联，同时调整了社会人口统计学特征、行为和临床因素以及抑郁症状。
在平均 6.6 年的随访期间，共有 557（6.9%）名参与者患上了心脏病。在控制了抑郁症状、行为和临床因素后，工作压力与女性患心脏病的风险增加相关（调整后的 HR=1.63，95%CI 1.02-2.64）。在男性中，工作压力与心脏病之间没有总体关联（调整后的 HR=0.96，95%CI 0.62-1.49）；仅在 50 岁及以上的男性中观察到这种关联。在那些从事体力劳动的人群中，心脏病和高度工作压力的发病率最高，而在那些从事专业工作的人群中发病率最低。
工作压力与中年女性以及 50 岁及以上男性患心脏病的风险增加有关。这种关联不能用抑郁症状或社会人口统计学、临床和行为因素来解释。
