Raftery S, Warde D
Department of Anaesthesia, Children's Hospital, Dublin, Ireland.
Br J Anaesth. 1990 Feb;64(2):167-9. doi: 10.1093/bja/64.2.167.
Anaesthesia was induced by inhalation in 100 children using nitrous oxide in oxygen supplemented by either halothane or isoflurane, with or without rectal thiopentone premedication. Respiratory problems occurred more frequently in the unpremedicated isoflurane group, resulting in significant reductions in oxygen saturation. Premedication reduced the frequency of these complications, and oxygen saturation was usually maintained.
对100名儿童采用吸入麻醉，吸入笑气及氧气，并辅以氟烷或异氟烷，部分儿童术前使用硫喷妥钠直肠给药。未进行术前给药的异氟烷组出现呼吸问题的频率更高，导致氧饱和度显著下降。术前给药降低了这些并发症的发生率，且氧饱和度通常能维持。
