Bannister J, McClure J H, Wildsmith J A
Department of Anaesthetics, Royal Infirmary, Edinburgh.
Br J Anaesth. 1990 Feb;64(2):232-4. doi: 10.1093/bja/64.2.232.
We have studied the effects of intrathecal injection of 0.5% bupivacaine in solutions containing different concentrations of glucose (0.33%, 0.83% and 8%) in three groups of 10 patients. The mean maximum extent of sensory block was significantly higher with 8% glucose (T3.6) than with 0.83% glucose (T7.2) or 0.33% glucose (T9.5). Administration of solutions containing 0.33% glucose produced a greater variability in upper level of sensory block (11 dermatomes) than the two other concentrations (six dermatomes each). The rate of onset of sensory block to T12 was fastest with solutions containing 8% glucose. Complete motor block of the legs was produced in every patient.
我们在三组每组10例患者中研究了鞘内注射含不同葡萄糖浓度（0.33%、0.83%和8%）的0.5%布比卡因溶液的效果。含8%葡萄糖的溶液（T3.6）的平均最大感觉阻滞范围显著高于含0.83%葡萄糖的溶液（T7.2）或含0.33%葡萄糖的溶液（T9.5）。含0.33%葡萄糖的溶液产生的感觉阻滞上限变异性（11个皮节）大于其他两种浓度（每种均为6个皮节）。含8%葡萄糖的溶液感觉阻滞至T12的起效速度最快。所有患者均出现腿部完全运动阻滞。
