Lee A, Ray D, Littlewood D G, Wildsmith J A
Department of Anaesthetics, Royal Infirmary, Edinburgh.
Br J Anaesth. 1988 Aug;61(2):135-8. doi: 10.1093/bja/61.2.135.
Effects of solutions of 0.5% amethocaine, containing different concentrations of dextrose (0%, 1.25%, 2.5% and 5%) were studied after intrathecal injection. The cephalad extent of block was greater with all three dextrose-containing solutions (T6), compared with the isobaric solution which contained no dextrose (T11). The variability of maximum level of block within each group was similar (seven dermatomes), and the rate of onset to maximum extent of block was the same in all groups. The rate of onset to the T12 dermatome was more rapid in the patients who received solutions containing dextrose. The initial onset of effect of the solution containing 1.25% dextrose was more like that of the isobaric solution than of those containing higher concentrations of dextrose.
鞘内注射后，研究了含不同浓度葡萄糖（0%、1.25%、2.5%和5%）的0.5%丁卡因溶液的效果。与不含葡萄糖的等比重溶液（T11）相比，含葡萄糖的三种溶液（T6）的阻滞头端范围更大。每组内阻滞最高平面的变异性相似（七个皮节），且所有组达到最大阻滞范围的起效速率相同。接受含葡萄糖溶液的患者中，达到T12皮节的起效速率更快。含1.25%葡萄糖溶液的初始起效更类似于等比重溶液，而不像含更高浓度葡萄糖的溶液。
