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本文引用的文献

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Successful H1N1 influenza vaccination of children receiving chemotherapy for solid tumors.实体瘤化疗儿童成功接种甲型H1N1流感疫苗。
J Pediatr Hematol Oncol. 2012 Aug;34(6):e228-31. doi: 10.1097/MPH.0b013e318241f7d9.
2
Immune response to 2009 pandemic H1N1 influenza virus A monovalent vaccine in children with cancer.儿童癌症患者对 2009 年甲型 H1N1 流感病毒单价疫苗的免疫反应。
Pediatr Blood Cancer. 2011 Dec 15;57(7):1154-8. doi: 10.1002/pbc.23113. Epub 2011 Mar 21.
3
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection.广泛交叉反应性抗体主导了人类针对 2009 年大流行 H1N1 流感病毒感染的 B 细胞反应。
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Poor immunogenicity of the H1N1 2009 vaccine in well controlled HIV-infected individuals.2009 年甲型 H1N1 流感疫苗在免疫控制良好的 HIV 感染者中的免疫原性差。
AIDS. 2010 Sep 10;24(14):2187-92. doi: 10.1097/QAD.0b013e32833c6d5c.
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Utility of influenza vaccination for oncology patients.流感疫苗对肿瘤患者的作用。
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Update on the 2009 pandemic influenza A H1N1 in children.儿童 2009 年大流行性流感 A(H1N1)更新。
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Immunogenicity of a monovalent 2009 influenza A(H1N1) vaccine in infants and children: a randomized trial.婴幼儿接种单价 2009 年甲型 H1N1 流感疫苗的免疫原性：一项随机试验。
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Response to a monovalent 2009 influenza A (H1N1) vaccine.对单价 2009 流感 A（H1N1）疫苗的反应。
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Use of influenza A (H1N1) 2009 monovalent vaccine: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009.2009年甲型H1N1流感单价疫苗的使用：免疫实践咨询委员会（ACIP）的建议，2009年
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Influenza vaccination in children being treated with chemotherapy for cancer.正在接受癌症化疗的儿童的流感疫苗接种
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绝对淋巴细胞计数可预测儿科癌症患者对新型甲型H1N1流感病毒疫苗接种的反应。

Absolute lymphocyte count predicts the response to new influenza virus H1N1 vaccination in pediatric cancer patients.

作者信息

Mavinkurve-Groothuis Annelies M C, van der Flier Michiel, Stelma Foekje, van Leer-Buter Coretta, Preijers Frank W, Hoogerbrugge Peter M

机构信息

Department of Pediatric Hematology and Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

出版信息

Clin Vaccine Immunol. 2013 Jan;20(1):118-21. doi: 10.1128/CVI.00585-12. Epub 2012 Nov 21.

DOI:10.1128/CVI.00585-12
PMID:23175288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3535770/
Abstract

We measured the vaccination response to the new H1N1 virus in relation to the lymphocyte count prior to vaccination in pediatric cancer patients. The absolute lymphocyte count above the lower normal limits (LNL) for age prior to vaccination predicts the response to influenza vaccination in pediatric cancer patients treated with chemotherapy.

摘要

我们测量了儿童癌症患者接种针对新型H1N1病毒疫苗后的反应，并将其与接种疫苗前的淋巴细胞计数进行关联。接种疫苗前高于年龄对应的正常下限（LNL）的绝对淋巴细胞计数可预测接受化疗的儿童癌症患者对流感疫苗接种的反应。