Thomas P, King K, Fraser W I, Kendell R E
Manchester Royal Infirmary.
Br J Psychiatry. 1990 Feb;156:204-10, 214-5. doi: 10.1192/bjp.156.2.204.
A computer-assisted analysis of samples of free speech from acute schizophrenics (n = 50), chronic schizophrenics (n = 27) and normal subjects (n = 50) enabled a comparison of the linguistic profiles of the three groups. The chronic group consistently emerged as the most impaired, on measures of complexity, integrity (error) and fluency of speech, with the acute patients performing less well than normal speakers but better than chronic patients. Demographic differences could account for only a small number of the linguistic differences. A comparison of chronic schizophrenics from the community and those from long-stay wards suggested that their poor linguistic performance was in some way related to the illness process and not to institutionalisation. Three possible explanations for these results were considered, particularly the possibility that low complexity of speech, negative symptoms and poor outcome are in some way related.
对50名急性精神分裂症患者、27名慢性精神分裂症患者和50名正常受试者的自由言语样本进行计算机辅助分析，从而对三组的语言特征进行比较。在言语的复杂性、完整性（错误）和流畅性方面，慢性组始终表现出受损最为严重，急性患者的表现不如正常说话者，但优于慢性患者。人口统计学差异只能解释少数语言差异。对社区慢性精神分裂症患者和长期住院病房患者的比较表明，他们较差的语言表现与疾病进程有关，而非机构化。针对这些结果考虑了三种可能的解释，尤其是言语复杂性低、阴性症状和不良预后在某种程度上相关的可能性。
