Department of Biomedical Engineering, University of California, Davis, Davis, CA 95616, USA.
Semin Nucl Med. 2013 Jan;43(1):19-29. doi: 10.1053/j.semnuclmed.2012.08.004.
Currently, the combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) as a hybrid imaging modality is receiving great attention not only in its emerging clinical applications but also in the preclinical field. Several prototypes based on several different types of PET detector technology have been developed in recent years, some of which have been used for first preclinical studies. This article provides an overview of currently available PET systems and considerations for combined PET/MRI workflows, and summarizes the results of the first studies performed on dedicated preclinical PET/MRI systems. The article also highlights other research using PET and MRI in combination and highlights potential benefits for integrated systems.
目前,正电子发射断层扫描(PET)和磁共振成像(MRI)的组合作为一种混合成像模式不仅在新兴的临床应用中受到极大关注,而且在临床前领域也受到极大关注。近年来已经开发出了几种基于几种不同类型的 PET 探测器技术的原型,其中一些已经用于首次临床前研究。本文概述了目前可用的 PET 系统和组合 PET/MRI 工作流程的注意事项,并总结了在专用临床前 PET/MRI 系统上进行的首次研究的结果。文章还强调了其他使用 PET 和 MRI 组合的研究,并突出了集成系统的潜在优势。