Upchurch R G, Elkan G H
Biochim Biophys Acta. 1978 Jan 18;538(2):244-8. doi: 10.1016/0304-4165(78)90352-5.
The effects of three factors (ammonia, L-glutamate, and cyclic adenosine 3',5'-monophosphate) on the ammonia assimilatory processes in aerobically grown Rhizobium japonicum colony derivatives were examined. Ammonia repressed glutamine synthetase activity and increased the average state of adenylylation of this enzyme. The addition of L-glutamate drastically decreased growth and strongly repressed glutamate synthase levels. Glutamine synthetase repression and adenylylation state were also increased by L-glutamate. The presence of cyclic AMP led to the repression of all three NH+4 assimilatory enzymes.
研究了三种因素（氨、L-谷氨酸和环腺苷酸3',5'-单磷酸）对需氧生长的日本根瘤菌菌落衍生物中氨同化过程的影响。氨抑制谷氨酰胺合成酶活性，并增加该酶的腺苷酸化平均状态。添加L-谷氨酸会显著降低生长，并强烈抑制谷氨酸合酶水平。L-谷氨酸还会增加谷氨酰胺合成酶的抑制作用和腺苷酸化状态。环腺苷酸的存在导致所有三种NH+4同化酶受到抑制。
