Levy M, Merritt A M, Levy L C
Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville.
Cornell Vet. 1990 Apr;80(2):143-51.
Isosmolar oral rehydrating solutions (ORS) used to treat diarrheic calves are low in energy. In contrast, hyperosmolar ORS may have a dehydrating effect. This study was designed to compare the net water and glucose absorption from the small intestine of normal calves given isosmolar or hyperosmolar ORS. Six calves were used for the experiment. A reentrant ileal cannula was implanted surgically. Each calf was fed with either the isosmolar or the hyperosmolar solution. The next day, the second solution was given. Both contained chromium EDTA as a nonabsorbable marker. Changes in the hematocrit, total plasma protein, plasma osmolality, plasma glucose concentration, and ileal volume, osmolality, glucose content, and chromium concentration were monitored for 10 hours. The only statistically significant difference was in the post-feeding plasma glucose level: it peaked at the higher level (p less than 0.05) in calves fed the hyperosmolar solution. In normal calves, the hyperosmolar ORS had no effect on the hydration or on the small intestinal fluid composition.
用于治疗腹泻犊牛的等渗口服补液盐（ORS）能量较低。相比之下，高渗ORS可能具有脱水作用。本研究旨在比较给正常犊牛投喂等渗或高渗ORS后，小肠对水和葡萄糖的净吸收情况。选用6头犊牛进行实验。通过手术植入一个回肠折返插管。每头犊牛分别投喂等渗溶液或高渗溶液。第二天，投喂另一种溶液。两种溶液均含有铬乙二胺四乙酸作为不可吸收标记物。在10小时内监测血细胞比容、总血浆蛋白、血浆渗透压、血浆葡萄糖浓度以及回肠容积、渗透压、葡萄糖含量和铬浓度的变化。唯一具有统计学显著差异的是投喂后血浆葡萄糖水平：在投喂高渗溶液的犊牛中，其峰值更高（p小于0.05）。在正常犊牛中，高渗ORS对水合作用或小肠液成分没有影响。
