Anthony Nolan Research Institute, Royal Free Hospital, Pond Street, Hampstead, London NW3 2QG, UK.
Nucleic Acids Res. 2013 Jan;41(Database issue):D1234-40. doi: 10.1093/nar/gks1140. Epub 2012 Nov 24.
The Immuno Polymorphism Database (IPD), http://www.ebi.ac.uk/ipd/ is a set of specialist databases related to the study of polymorphic genes in the immune system. The IPD project works with specialist groups or nomenclature committees who provide and curate individual sections before they are submitted to IPD for online publication. The IPD project stores all the data in a set of related databases. IPD currently consists of four databases: IPD-KIR, contains the allelic sequences of killer-cell immunoglobulin-like receptors, IPD-MHC, a database of sequences of the major histocompatibility complex of different species; IPD-HPA, alloantigens expressed only on platelets; and IPD-ESTDAB, which provides access to the European Searchable Tumour Cell-Line Database, a cell bank of immunologically characterized melanoma cell lines. The data is currently available online from the website and FTP directory. This article describes the latest updates and additional tools added to the IPD project.
免疫多态性数据库(IPD),http://www.ebi.ac.uk/ipd/ 是一组与免疫系统中多态基因研究相关的专业数据库。IPD 项目与专业小组或命名委员会合作,在将各个部分提交给 IPD 进行在线发布之前,由他们提供和管理这些部分。IPD 项目将所有数据存储在一组相关的数据库中。IPD 目前由四个数据库组成:IPD-KIR,包含杀伤细胞免疫球蛋白样受体的等位基因序列;IPD-MHC,不同物种主要组织相容性复合体的序列数据库;IPD-HPA,仅在血小板上表达的同种异体抗原;以及 IPD-ESTDAB,可访问欧洲可搜索肿瘤细胞系数据库,这是一个免疫特性明确的黑色素瘤细胞系的细胞库。该数据目前可从网站和 FTP 目录在线获取。本文介绍了 IPD 项目的最新更新和添加的其他工具。