Cardiac Center, University Hospital of Cologne, Germany.
Dtsch Arztebl Int. 2012 Oct;109(43):727-32. doi: 10.3238/arztebl.2012.0727. Epub 2012 Oct 26.
Ruptured abdominal aortic aneurysm (rAAA) remains a challenging problem: 2,410 cases were treated in Germany in 2010. Ruptured abdominal aortic aneurysm should be suspected in patients over age 50 who complain of pain in the abdomen or back and in whom examination reveals a pulsatile abdominal mass. The incidence of hospitalization for rAAA is 12 per 100,000 persons over age 65 per year (statistics for Germany, 2010), and rAAA carries an overall mortality of 80%.
The current state of knowledge of rAAA was surveyed in a selective review of pertinent literature retrieved by an electronic search in the PubMed, Web of Science, and Cochrane Library databases with the keywords "abdominal aortic aneurysm," "ruptured," "open repair," and "endovascular." Publications in English or German up to and including March 2012 were considered, among them the Clinical Practice Guidelines of the European Society for Vascular Surgery (1).
Recent reports show that the treatment of rAAA is still fraught with high mortality and high perioperative morbidity. Improvement is needed. It would be advisable for the care of rAAA to be centralized in specialized vascular centers implementing defined treatment pathways. Systematic screening, too, would be beneficial. An increasing number of reports suggest that endovascular treatment with stent prostheses improves outcomes; more definitive evidence on this matter will come from prospective, randomized trials that are now in progress.
破裂性腹主动脉瘤(rAAA)仍然是一个具有挑战性的问题:2010 年在德国治疗了 2410 例。破裂性腹主动脉瘤应怀疑在年龄超过 50 岁的患者谁抱怨腹痛或背部疼痛和检查显示在腹部搏动性肿块。rAAA 的住院发病率为每年每 10 万人 12 例(德国统计数据,2010 年),rAAA 的总体死亡率为 80%。
通过在 PubMed、Web of Science 和 Cochrane Library 数据库中使用关键词“腹主动脉瘤”、“破裂”、“开放修复”和“血管内”进行电子搜索,选择性地回顾了相关文献,调查了 rAAA 的最新知识状态。考虑到 2012 年 3 月之前发表的英文或德文出版物,其中包括欧洲血管外科学会的临床实践指南(1)。
最近的报告表明,rAAA 的治疗仍然存在高死亡率和高围手术期发病率。需要改进。将 rAAA 的护理集中在专门的血管中心实施明确的治疗途径是明智的。系统筛查也将是有益的。越来越多的报告表明,支架假体的血管内治疗可改善结果;这方面更明确的证据将来自正在进行的前瞻性、随机试验。