小动物葡萄球菌中的抗菌药物耐药性

Antimicrobial resistance in staphylococci in small animals.

作者信息

Cain Christine L

机构信息

Department of Clinical Studies-Philadelphia, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2013 Jan;43(1):19-40. doi: 10.1016/j.cvsm.2012.09.003.

DOI:10.1016/j.cvsm.2012.09.003

PMID:23182322

Abstract

Staphylococcal antimicrobial resistance presents an emerging challenge for both human and veterinary medical professionals. Infections associated with methicillin- and multidrug-resistant staphylococci are increasingly encountered by veterinarians and are frequently associated with empiric therapeutic failures and limited systemic antimicrobial options. This article addresses mechanisms of antimicrobial resistance in common staphylococcal pathogens and implications for clinical practice, including indications for culture and susceptibility testing, rational antimicrobial selection, and potential for zoonotic transmission.

摘要

葡萄球菌的抗菌耐药性对人类和兽医医学专业人员来说都是一个新出现的挑战。兽医越来越多地遇到与耐甲氧西林和多重耐药葡萄球菌相关的感染，这些感染常常与经验性治疗失败以及有限的全身抗菌药物选择有关。本文探讨常见葡萄球菌病原体的抗菌耐药机制及其对临床实践的影响，包括培养和药敏试验的指征、合理选择抗菌药物以及人畜共患病传播的可能性。